1Meta-Analysis2021
de Araujo DP, Pereira PTVT, Fontes AJC, Marques KDS, de Moraes ÉB, Guerra RNM · Support Care Cancer (2021)
No plain-language summary recorded for this citation — open the paper to read its abstract.
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23 peer-reviewed studies
What the evidence says
Most Guarana studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 2006–2026 with a typical study size of 229 participants.
Based on 23 studies · 4 meta-analyses · 15 RCTs · 2,351 total participants
Confidence
High confidenceBy outcome
13 studies in the last 5 years · Latest meta-analysis: 2024
de Araujo DP, Pereira PTVT, Fontes AJC, Marques KDS, de Moraes ÉB, Guerra RNM · Support Care Cancer (2021)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Gurney T, Ronca F · Nutrients (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Hack B, Penna EM, Talik T, Chandrashekhar R, Millard-Stafford M · Nutrients (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Kennedy DO, Haskell CF, Robertson B, Reay J, Brewster-Maund C, Luedemann J · Appetite (2008)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Scholey A, Bauer I, Neale C, Savage K, Camfield D, White D · Nutrients (2013)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Gurney T, Bradley N, Izquierdo D, Ronca F · Br J Nutr (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Sette CVM, Ribas de Alcântara BB, Schoueri JHM, Cruz FM, Cubero DIG, Pianowski LF · J Diet Suppl (2018)
No plain-language summary recorded for this citation — open the paper to read its abstract.
de Oliveira Campos MP, Riechelmann R, Martins LC, Hassan BJ, Casa FB, Del Giglio A · J Altern Complement Med (2011)
No plain-language summary recorded for this citation — open the paper to read its abstract.
del Giglio AB, Cubero Dde I, Lerner TG, Guariento RT, de Azevedo RG, Paiva H · J Diet Suppl (2013)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Pomportes L, Davranche K, Brisswalter I, Hays A, Brisswalter J · Nutrients (2014)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Leonard M, Maury J, Dickerson B, Gonzalez DE, Kendra J, Jenkins V · Nutrients (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Silvestrini GI, Marino F, Cosentino M · J Negat Results Biomed (2013)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Sale C, Harris RC, Delves S, Corbett J · Int J Obes (Lond) (2006)
No plain-language summary recorded for this citation — open the paper to read its abstract.
da Costa Miranda V, Trufelli DC, Santos J, Campos MP, Nobuo M, da Costa Miranda M · J Altern Complement Med (2009)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Wang L, Xu X, Guo M, Dong Y, Ding H, Hao S, Huo L, Song Y, Gu J, Yu Z. · Frontiers in pharmacology (2025)
In plain English: Well-designed, multicenter trials are essential to determine whether phytotherapy can meaningfully contribute to CRF management.
Matsas S, Medeiros Araujo de Matos U, Molina Llata C, Del Giglio A. · Diseases (Basel, Switzerland) (2026)
In plain English: Excessive EDs consumption poses a real cardiotoxic risk, especially in vulnerable populations, underscoring the need for further human research and potential regulatory consideration.
Ghamlouch A, Di Fazio N, Racciatti M, Del Duca F, Treves B, De Angelis G, De Matteis A, Maiese A, Frati P. · Cardiovascular toxicology (2025)
In plain English: Conclusion Acute ingestion of guarana improves the capacity to perform intermittent exercise in soccer players but seems to be ineffective to improve lower limb power, sprint, and agility.
Estrázulas JA, Pereira Dos Santos F, Taborda Machado AJ, Legnani E, Bertuzzi R, Lima-Silva AE. · Journal of the American Nutrition Association (2024)
In plain English: Conclusion "WKUP GT" showed improvements for attention, memory, psychomotor and executive function tasks after lunch without increase in pulse rate.
Nadam IS, Bellamine A, Salom R, Guilera S, Inarejos-Garcia AM, Pillar G. · Human psychopharmacology (2024)
In plain English: The primary ergogenic nutrients in most energy drinks appear to be caffeine and/or carbohydrate; additive benefits of other ingredients like guarana remain to be determined.
Jagim AR et al. · J Int Soc Sports Nutr (2023)