63 peer-reviewed studies · Evidence score: 9/10
Drugeon B et al. • JAMA network open (2026)
In this NMA of RCTs, high concentration CHG in isopropyl alcohol was associated with the lowest incidence of CRIs.
He Q et al. • Australian critical care : official journal of the Confederation of Australian Critical Care Nurses (2025)
Antimicrobial mouthwashes, especially chlorhexidine, pose potential risks in ICU patients; oxidising solutions demonstrate relative safety.
Machinski E et al. • The Journal of arthroplasty (2025)
In this meta-analysis, chlorhexidine and povidone-iodine had a significantly reduced risk of PJI as compared with saline irrigation in total joint arthroplasty.
Greenwood DC et al. • Nutrients (2023)
Whilst associations were modest-sized, we recommend maintaining iodine sufficiency in the population, especially for women of childbearing age on restricted diets low in iodide.
Eveleigh ER et al. • The British journal of nutrition (2023)
Further research into the usefulness of mandatory fortification of vegan appropriate foods is required.
Li L et al. • International journal of nursing studies (2022)
In comparison to povidone-iodine, chlorhexidine showed better results in preventing postoperative SSI.
Zhang X et al. • Frontiers in endocrinology (2022)
The 10 case-control included studies involved a total of 6,544 participants.
Zhang F et al. • Journal of wound care (2021)
This review and meta-analysis demonstrate beneficial effects of honey-based dressings over povidone iodine-based dressings for wound recovery.
Santos JAR et al. • The Cochrane database of systematic reviews (2019)
The evidence on the effect of iodine fortification of foods, beverages, condiments, or seasonings other than salt on reducing goitre, improving physical development measures, and any adverse effects is uncertain.
Chen S et al. • World journal of surgery (2020)
Chlorhexidine was superior to povidone-iodine in preventing postoperative SSI, especially for the clean-contaminated surgery.
Wang B et al. • Frontiers in endocrinology (2025)
This meta-analysis confirmed the role of BRAFV600E mutation in deterioration of the ability of RAI uptake but provided insufficient evidence to demonstrate that BRAFV600E mutation might impact the clinical response and recurrence after postsurgical RAI therapy for PTC patients.
Gräfe W et al. • Journal of endocrinological investigation (2025)
This systematic review and meta-analysis indicate that iodine deficiency increases moderately the risk of developing thyroid nodules, while more than adequate and excessive iodine intake does not show a consistent effect.
Bolakale-Rufai IK et al. • Sao Paulo medical journal = Revista paulista de medicina (2023)
The use of methimazole before radioactive iodine administration was not associated with an increased risk of persistent hyperthyroidism.
Nazeri P et al. • The American journal of clinical nutrition (2016)
Our findings reveal that, compared with heel blood samples, neonatal thyrotropin in samples collected from the cord are more sensitive to the iodine status of mothers; however, further investigations are required in this regard.
Candido AC et al. • Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) (2023)
Daily iodine supplementation had satisfactory effects on iodine status and maternal thyroid hormone concentrations.
Bhandari A et al. • Clinical radiology (2023)
Spectral CT shows promise in differentiating focal liver lesions.
Azevedo FM et al. • Biological trace element research (2023)
The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
González Martín-Moro J et al. • Contact lens & anterior eye : the journal of the British Contact Lens Association (2023)
At this time there is great uncertainty about the usefulness of PI on the course of adenoviral conjunctivitis.
Candido AC et al. • Biological trace element research (2023)
The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Jiang Y et al. • BMJ open (2024)
Silver dressings, demonstrating a comparable healing rate to iodine dressings, significantly reduce healing time, suggesting their potential as a superior adjunct in wound care.