1Meta-Analysis2017
Ursoniu S, Sahebkar A, Serban MC, Antal D, Mikhailidis DP, Cicero A · Nutr Rev (2017)
No plain-language summary recorded for this citation — open the paper to read its abstract.
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53 peer-reviewed studies
What the evidence says
Most Krill Oil studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 2003–2026 with a typical study size of 115 participants.
Based on 53 studies · 7 meta-analyses · 38 RCTs · 8,249 total participants
Confidence
High confidenceBy outcome
33 studies in the last 5 years · Latest meta-analysis: 2026
Ursoniu S, Sahebkar A, Serban MC, Antal D, Mikhailidis DP, Cicero A · Nutr Rev (2017)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Kim MG, Yang I, Lee HS, Lee JY, Kim K · Nutr Rev (2020)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Huang H, Liao D, He B, Zhou G, Cui Y · Diabetes Metab Syndr (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
In plain English: The study findings will be disseminated through peer-reviewed publications, scientific conferences and channels aimed at the general public.
de Abreu-Silva EO et al. · BMJ open (2026)
In plain English: Krill oil is a promising functional food with a favorable safety profile for KOA symptom management, particularly for pain and physical function.
Kou H et al. · Inflammopharmacology (2026)
In plain English: It explores its influence on glucose homeostasis, oxidative stress responses, inflammatory pathways, lipid metabolism, and muscle physiology.
Attri N, Arora D, Saini R, Chandel M, Suthar P, Dhiman A. · Food science and biotechnology (2025)
In plain English: Formulations with high amounts of DHA in the form of PLs offer higher bioavailability but are more expensive than other formulations.
Alvear I, Duarte L, Farias C, Videla LA, Muñoz Y, Valenzuela R. · Critical reviews in food science and nutrition (2026)
In plain English: Based on these findings, krill oil supplementation is not yet justified for knee pain.
Pimentel T, Queiroz I, Florêncio de Mesquita C, Gallo Ruelas M, Leandro GN, Ribeiro Monteiro A, Nunes Pimentel F. · Inflammopharmacology (2024)
In plain English: Conclusion Krill oil presents as a promising safe therapeutic option for knee osteoarthritis; however, its efficacy in pain relief requires further investigation.
Meng J, Wang X, Li Y, Xiang Y, Wu Y, Xiong Y, Liu P, Gao S. · Medicine (2025)
In plain English: However, further large-scale, well-designed randomized controlled trials (RCTs) are needed to confirm these findings, particularly those that include more standardized dosages and formulations, as well as to evaluate their long-term efficacy.
Zhang Y, Gui Y, Adams R, Farragher J, Itsiopoulos C, Bow K, Cai M, Han J. · Nutrients (2025)
Maki KC, Reeves MS, Farmer M, Griinari M, Berge K, Vik H · Nutr Res (2009)
No plain-language summary recorded for this citation — open the paper to read its abstract.
van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM · Prostaglandins Leukot Essent Fatty Acids (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Köhler A, Sarkkinen E, Tapola N, Niskanen T, Bruheim I · Lipids Health Dis (2015)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Sampalis F, Bunea R, Pelland MF, Kowalski O, Duguet N, Dupuis S · Altern Med Rev (2003)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Hill WS, Dohnalek MH, Ha Y, Kim SJ, Jung JC, Kang SB · Nutrients (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Schuchardt JP, Schneider I, Meyer H, Neubronner J, von Schacky C, Hahn A · Lipids Health Dis (2011)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Bunea R, El Farrah K, Deutsch L · Altern Med Rev (2004)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Deutsch L · J Am Coll Nutr (2007)
No plain-language summary recorded for this citation — open the paper to read its abstract.
van der Wurff IS, von Schacky C, Berge K, Zeegers MP, Kirschner PA, de Groot RH · Nutrients (2016)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Lobo PCB, Roriz LN, Siqueira JM, Giglio BM, Marini ACB, Corgosinho FC · Int J Environ Res Public Health (2022)
No plain-language summary recorded for this citation — open the paper to read its abstract.