1Meta-Analysis2015
Chanson-Rolle A, Aubin F, Braesco V, Hamasaki T, Kitakaze M · PLoS One (2015)
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34 peer-reviewed studies
What the evidence says
Most Lactotripeptides studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 2004–2021.
Based on 34 studies · 7 meta-analyses · 25 RCTs
Confidence
High confidenceBy outcome
Only 1 study in the last 5 years · Latest meta-analysis: 2015
Chanson-Rolle A, Aubin F, Braesco V, Hamasaki T, Kitakaze M · PLoS One (2015)
Fekete ÁA, Givens DI, Lovegrove JA · Nutrients (2015)
Qin LQ, Xu JY, Dong JY, Zhao Y, van Bladeren P, Zhang W · Nutr Metab Cardiovasc Dis (2013)
Cicero AF, Gerocarni B, Laghi L, Borghi C · J Hum Hypertens (2011)
Turpeinen AM, Järvenpää S, Kautiainen H, Korpela R, Vapaatalo H · Ann Med (2013)
Cicero AF, Aubin F, Azais-Braesco V, Borghi C · Am J Hypertens (2013)
van der Zander K, Bots ML, Bak AA, Koning MM, de Leeuw PW · Am J Clin Nutr (2008)
Jauhiainen T, Niittynen L, Orešič M, Järvenpää S, Hiltunen TP, Rönnback M · Eur J Clin Nutr (2012)
Ishida Y, Shibata Y, Fukuhara I, Yano Y, Takehara I, Kaneko K · Biosci Biotechnol Biochem (2011)
Engberink MF, Schouten EG, Kok FJ, van Mierlo LA, Brouwer IA, Geleijnse JM · Hypertension (2008)
Turpeinen AM, Ikonen M, Kivimäki AS, Kautiainen H, Vapaatalo H, Korpela R · Food Funct (2012)
Yoshizawa M, Maeda S, Miyaki A, Misono M, Choi Y, Shimojo N · Am J Physiol Heart Circ Physiol (2009)
Jauhiainen T, Rönnback M, Vapaatalo H, Wuolle K, Kautiainen H, Groop PH · Eur J Clin Nutr (2010)
Cicero AF, Rosticci M, Ferroni A, Bacchelli S, Veronesi M, Strocchi E · Clin Exp Hypertens (2012)
Tuomilehto J, Lindström J, Hyyrynen J, Korpela R, Karhunen ML, Mikkola L · J Hum Hypertens (2004)
Nakamura T, Mizutani J, Ohki K, Yamada K, Yamamoto N, Takeshi M · Atherosclerosis (2011)
Igase M, Okada Y, Igase K, Matsumoto S, Senzaki K, Ochi M · Rejuvenation Res (2021)
Sano J, Ohki K, Higuchi T, Aihara K, Mizuno S, Kajimoto O · J Med Food (2005)
Germino FW, Neutel J, Nonaka M, Hendler SS · J Clin Hypertens (Greenwich) (2010)
Mizuno S, Matsuura K, Gotou T, Nishimura S, Kajimoto O, Yabune M · Br J Nutr (2005)