1Meta-Analysis2021
Qin Y · J Gynecol Obstet Hum Reprod (2021)
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99 peer-reviewed studies
What the evidence says
Letrozole doesn't have enough studies with structured effect-size data yet to pool a verdict. Browse the studies below for individual findings.
Most evidence is from high-quality meta-analyses and randomised trials published 2003–2026 with a typical study size of 42 participants.
Based on 99 studies · 21 meta-analyses · 70 RCTs · 7,368 total participants
Confidence
High confidenceBy outcome
59 studies in the last 5 years · Latest meta-analysis: 2026
Qin Y · J Gynecol Obstet Hum Reprod (2021)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Tang X, Huang Q, Wang C, Zhang D, Dong S, Yu C · Front Endocrinol (Lausanne) (2021)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Baradwan S, Al-Shalhoub F, Alshahrani MS, Himayda S, AlSghan R, Sabban H · Hormones (Athens) (2024)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Zhao J, Xu B, Huang X, Yan Y, Li Y · Reprod Health (2020)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Dutta D, Singla R, Surana V, Sharma M · J Clin Res Pediatr Endocrinol (2022)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Tarafdari A, Keikha F, Asadi F, Hantoushzadeh S, Gargari OK, Forouzin M · Reprod Sci (2024)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Zeng MF, Zhou X, Duan JL · Gynecol Endocrinol (2021)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Sun S, Zhang H, Zhong P, Xu Z · Biomed Res Int (2021)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Miller KAR, de Castro Martin GC, Servidoni ACP, Dos Santos PL, Lemos MJ, Pereira H · Eur J Contracept Reprod Health Care (2026)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Bülow NS, Wissing ML, Macklon N, Pinborg A, Løssl K · Hum Reprod Update (2025)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Cai T, Al-Jubairi NN, Santos HO, de Souza IGO, Chen Y · Steroids (2021)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Etrusco A, D'Amato A, Agrifoglio V, Laganà AS, Andrisani A, Cantatore C · Eur J Obstet Gynecol Reprod Biol (2025)
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Laganà AS, Etrusco A, Haydamous J, Semaan S, Agrifoglio V, Chiantera V · Eur J Obstet Gynecol Reprod Biol (2024)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Zhang T, Feng F, Yao Y, Qi L, Tian J, Zhou C · J Cell Physiol (2019)
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Marchetti C, De Felice F, Ergasti R, Scambia G, Fagotti A · Int J Gynecol Cancer (2020)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Nash CM, Philp L, Shah P, Murphy KE · Contraception (2018)
No plain-language summary recorded for this citation — open the paper to read its abstract.
In plain English: Our results support lower-dose combination therapy for improved ovulation, follicle count, and pregnancy outcomes while reducing miscarriage risk.
Alhebshi ZA, Alqarni DH, Najjar AA, Alshalahi SS, Alhatlani RA, Jamal A, Wasaya HMI, Almehmadi M, Alrafi MA, AlHabardi N. · Reproductive sciences (Thousand Oaks, Calif.) (2025)
Allameh Z, Goharian M, Eslamian M · Int J Gynaecol Obstet (2020)
No plain-language summary recorded for this citation — open the paper to read its abstract.
van 't Veer LJ, Meershoek-Klein Kranenbarg E, Duijm-de Carpentier M, Van de Velde CJH, Kleijn M, Dreezen C · JAMA Netw Open (2024)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Elfrink EM, Johannsen ML, Pedersen KM, la Cour Poulsen L, Zheng M, Grøndahl ML · J Assist Reprod Genet (2026)
No plain-language summary recorded for this citation — open the paper to read its abstract.