Li CP, Gau SY, Chen CC, Kao CH, Tsai RY, Yang HJ · In Vivo (2024)
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27 peer-reviewed studies
What the evidence says
Most Manuka Honey studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 2004–2026.
Based on 27 studies · 2 meta-analyses · 17 RCTs
Confidence
High confidence14 studies in the last 5 years · Latest meta-analysis: 2024
Li CP, Gau SY, Chen CC, Kao CH, Tsai RY, Yang HJ · In Vivo (2024)
Hu J, Kong L, Zhu S, Ju M, Zhang Q · Clin Exp Optom (2023)
Kuitunen I, Renko M · Eur J Pediatr (2023)
Lee VS, Humphreys IM, Purcell PL, Davis GE · Clin Otolaryngol (2021)
Hawley P, Hovan A, McGahan CE, Saunders D · Support Care Cancer (2014)
Craig JP, Cruzat A, Cheung IMY, Watters GA, Wang MTM · Ocul Surf (2020)
Wallace A, Eady S, Miles M, Martin H, McLachlan A, Rodier M · Br J Nutr (2010)
Jain A, Singh V, Lukram A, Chatterjee S, Khan AM, Dawar G · Indian J Dent Res (2022)
Tan J, Jia T, Liao R, Stapleton F · Br J Ophthalmol (2020)
Dagher H, Hachem RY, Hakim C, Husni R, Hammoudeh DS, Karroum MB · Int Wound J (2026)
Ooi ML, Jothin A, Bennett C, Ooi EH, Vreugde S, Psaltis AJ · Int Forum Allergy Rhinol (2019)
Li AL, Li SL, Kam KW, Young AL · Br J Ophthalmol (2022)
Henatsch D, Wesseling F, Briedé JJ, Stokroos RJ · Otol Neurotol (2015)
Johnson DW, Badve SV, Pascoe EM, Beller E, Cass A, Clark C · Lancet Infect Dis (2014)
Fogh SE, Deshmukh S, Berk LB, Dueck AC, Roof K, Yacoub S · Int J Radiat Oncol Biol Phys (2017)
Bardy J, Molassiotis A, Ryder WD, Mais K, Sykes A, Yap B · Br J Oral Maxillofac Surg (2012)
Badr LK, El Asmar R, Hakim S, Saad R, Merhi R, Zahreddine A · J Pediatr Nurs (2023)
Alasqah M, Alrashidi A, Alshammari N, Alshehri A, Gufran K · Eur Rev Med Pharmacol Sci (2022)
English HK, Pack AR, Molan PC · J Int Acad Periodontol (2004)
In plain English: This review explores honey's composition and therapeutic potential, emphasizing its rich bioactive profile, which continues to attract scientific interest for treating various health conditions and promoting overall well-being.
Bolat E, Canbolat AA, Sarıtaş S, Lombardo M, Witkowska AM, El-Seedi H, Bechelany M, Karav S. · Food science & nutrition (2026)