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Evidence-based supplements similar to Minoxidil (oral & topical), ranked by shared goals and clinical evidence. Compare any of them head-to-head below.
A prescription 5α-reductase type-II inhibitor that lowers DHT to treat male pattern hair loss (1 mg, Propecia) and benign prostatic hyperplasia (5 mg, Proscar). The hair and prostate benefits are well-proven in large RCTs. The honest caveats are real and prominent: sexual side effects (erectile dysfunction, decreased libido) in a minority of men, a disputed but important 'post-finasteride syndrome' with persistent symptoms, and a depression/suicidality safety signal in pharmacovigilance data. It is NOT a longevity drug.
A dual 5α-reductase (type I + II) inhibitor approved for benign prostatic hyperplasia and used off-label for male pattern hair loss. It suppresses DHT more deeply than finasteride (which blocks only type II), and head-to-head it beats finasteride for hair regrowth. It carries the same sexual and mood side-effect concerns as finasteride — with a much longer half-life, so any persistent effects clear more slowly. A prescription drug, not a supplement, and not a longevity drug.
The same drug as oral finasteride, applied to the scalp — with a systemic-sparing claim that the pharmacokinetic data only partly supports.
This information is for educational purposes only. It is not a substitute for professional medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication.