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Olive Leaf Extract (Oleuropein)
Oleuropein-rich extract with antiviral, antibacterial, and blood pressure-lowering effects — part of the Mediterranean diet's protective profile.
What the evidence says
Olive Leaf Extract appears to help in 9 of 11 studies with measurable effects — the evidence leans clearly favourable.
Most evidence is from high-quality meta-analyses and randomised trials published 2009–2026 with a typical study size of 74 participants.
Based on 44 studies · 5 meta-analyses · 27 RCTs · 6,197 total participants
Confidence
HighWhat the studies found
By outcome
Olive Leaf Extract has an evidence score of 8.5/10 — very strong evidence based on 44 indexed studies, including 3 meta-analyses. Oleuropein-rich extract with antiviral, antibacterial, and blood pressure-lowering effects — part of the Mediterranean diet's protective profile.
The commonly studied dose of Olive Leaf Extract is 500-1000mg (standardized to 15-20% oleuropein). Research points to an estimated optimal dose around 1000mg, with a minimum effective dose near 500mg. Individual response varies — start low and adjust.
The best time to take Olive Leaf Extract is with meals. Taking it with food is preferred. Olive leaf extract contains oleuropein and hydroxytyrosol, polyphenols with cardiovascular and antimicrobial properties.
Last reviewed May 2026 · evidence from 40 studies · how we score
This information is for educational purposes only. It is not a substitute for professional medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication.
Olive Leaf Extract contains oleuropein and other polyphenols that provide antimicrobial, antioxidant, and cardiovascular benefits. Used traditionally for infections and immune support, modern research confirms antiviral, antibacterial, and blood pressure benefits. Part of the Mediterranean diet's protective effects.
Direct action against bacteria, viruses, and fungi
Helps relax blood vessels
How Olive Leaf Extract works — from molecular targets to health outcomes. Click an edge to see supporting research.This visualization is in beta — pathways are being refined and expanded.
500-1000mg (standardized to 15-20% oleuropein)
Take with food
| Form | Type |
|---|---|
| 💊Standardized extract (15-20% oleuropein) | Recommended |
| 💊Dried leaf | Alternative |
| 💧Tincture | Alternative |
Standardized extracts are more consistent. Higher oleuropein content means higher potency.
Minimum: 4 weeks
Optimal: 8 weeks
Cycling: Not required
Note: Can be taken any time. Split dosing (2-3 times daily) may be beneficial.
Based on RCT showing 6.4 mmHg SBP reduction, but one crossover trial showed no effect. Mixed results suggest conservative effectiveness estimates. Primarily studied in hypertensive populations.
Enhanced resistance to infections
Modest BP reduction
Insufficient data; consult doctor
May have additive effects
May affect blood sugar
Tip: Take with food
Tip: Start with lower dose
Olive Leaf Extract is generally well-tolerated and considered safe for most healthy adults at recommended doses. The most commonly reported side effects are GI upset, herxheimer reaction (die-off). Use caution if any of these apply to you: Known allergy or hypersensitivity to Olive Leaf Extract or related compounds; Pregnancy and breastfeeding; Low blood pressure (may lower BP further).
Beta-Sitosterol
Likely helpsPlant sterol that reduces BPH urinary symptoms in clinical trials and blocks intestinal cholesterol absorption.
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