Ox Bile Extract
Supplemental bile acids that restore fat digestion and fat-soluble vitamin absorption after gallbladder removal or bile insufficiency.
Ox Bile provides supplemental bile acids for people who have had their gallbladder removed or who have insufficient bile production. Bile is essential for digesting and absorbing dietary fats and fat-soluble vitamins. Without adequate bile, people experience fatty food intolerance, bloating, and nutrient malabsorption.
Breaks down fats into smaller droplets
Enables absorption of vitamins A, D, E, K
How Ox Bile works — from molecular targets to health outcomes. Click an edge to see supporting research.This visualization is in beta — pathways are being refined and expanded.
100-500mg with fatty meals
Loading: Start with lower dose and adjust based on fat content of meal
Take with food
| Form | Type |
|---|---|
| 💊Ox bile capsules | Recommended |
| 💊Combination digestive enzymes with bile | Alternative |
| 💊Bile salts | Alternative |
Often combined with lipase for enhanced fat digestion.
Minimum: 1 weeks
Optimal: 4 weeks
Cycling: Not required
Note: Only needed with meals containing significant fat. Dose based on meal fat content.
Less discomfort after fatty meals
Improved absorption of fat-soluble vitamins
Less post-meal bloating and discomfort
Primary indication; often very helpful
Tip: Reduce dose
Tip: Take with food
Top studies from 10+ peer-reviewed papers
Tang B et al. • Nature communications (2025)
“This observational examined the effects of Ox Bile.”
Bhargava P et al. • The Journal of clinical investigation (2020)
“These findings identify dysregulated bile acid metabolism as a potential therapeutic target in MS.”
Madden SK et al. • Clinical nutrition (Edinburgh, Scotland) (2020)
“Lifestyle interventions are a promising treatment for psoriasis and its associated co-morbidities.”
Singh N et al. • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (2016)
“Subsequently, all fractions were tested for their anti-oxidative property on HepG2 cells exposed to H2O2 that served as an oxidative injury model.”
Svoboda MD et al. • American journal of medical genetics. Part C, Seminars in medical genetics (2012)
“We review the current literature and expert opinion on treatments for SLOS and other selected sterol disorders, including dietary cholesterol therapy, statin treatment, bile acid supplementation, medical therapies, and surgical interventions, as well as directions for future therapies and treatment research.”
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