We use essential cookies (authentication, your saved goals/stack) by default. With your permission we’ll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more about cookies

Oxa4.7

Oxandrolone (Anavar) Research

Mostly mechanism / observational

82 peer-reviewed studies

What the evidence says

Mostly mechanism / observational

Most Oxandrolone (Anavar) studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.

Most evidence is from high-quality meta-analyses and randomised trials published 1976–2025 with a typical study size of 133 participants.

Based on 82 studies · 5 meta-analyses · 74 RCTs · 199 total participants

Confidence

High confidence

By outcome

Hormones & virilization
Mostly mechanism / observational15 studies
Wound healing & burns
Mostly mechanism / observational13 studies
Liver & hepatotoxicity
Mostly mechanism / observational7 studies
Lean mass & muscle wastingIn severe burns, RCTs and a 15-trial meta-analysis show oxandrolone adds lean body mass and reduces nitrogen loss; a randomized HIV trial showed dose-dependent gains in body cell mass · Weeks to months
Mostly mechanism / observational5 studies
Safety profile
Mostly mechanism / observational3 studies

Slowing down

Only 2 studies in the last 5 years · Latest meta-analysis: 2025

197620002025

1Meta-Analysis2019

Asehnoune K, Vourc'h M, Roquilly A · Crit Care Clin (2019)

Oxandrolone (Anavar) Research

Mostly mechanism / observational

Hormone Therapy in Trauma Patients.

The efficacy and safety of oxandrolone treatment for patients with severe burns: A systematic review and meta-analysis.

Oxandrolone use in adult burn patients. Systematic review and meta-analysis.

Oxandrolone in the Treatment of Burn Injuries: A Systematic Review and Meta-analysis.

Oxandrolone for burn patients: a systematic review and updated meta-analysis of randomized controlled trials from 2005 to 2025.

Anabolic steroids for treating pressure ulcers.

Effects of androgen therapy on adipose tissue and metabolism in older men.

Three-year results of treatment with growth hormone, alone or associated with oxandrolone, in girls with Turner syndrome. The Kabi Collaborative Study Group.

Oxandrolone Coadministration Does Not Alter Plasma Propranolol Concentrations in Severely Burned Pediatric Patients.

Propranolol and Oxandrolone Therapy Accelerated Muscle Recovery in Burned Children.

Reversal of Growth Arrest With the Combined Administration of Oxandrolone and Propranolol in Severely Burned Children.

Effect of low dose oxandrolone and testosterone treatment on the pituitary-testicular and GH axes in boys with constitutional delay of growth and puberty.

Androgen treatment effects on hippocampus structure in boys with Klinefelter syndrome.

Five-year outcomes after oxandrolone administration in severely burned children: a randomized clinical trial of safety and efficacy.

Oxandrolone Augmentation of Resistance Training in Older Women: A Randomized Trial.

Growth and growth hormone responses to oxandrolone in boys with constitutional delay of growth and puberty (CDGP).

Effect of oxandrolone and timing of pubertal induction on final height in Turner's syndrome: randomised, double blind, placebo controlled trial.

Karyotype-specific ear and hearing problems in young adults with Turner syndrome and the effect of oxandrolone treatment.

The effect of short-term growth hormone or low-dose oxandrolone treatment in boys with constitutional growth delay.

Oral treatment for constitutional delay of growth and puberty in boys: a randomised trial of an anabolic steroid or testosterone undecanoate.