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Pgn6.0
Panax Ginseng Research
Likely helps
260 peer-reviewed studies
What the evidence says
Likely helps
Panax Ginseng appears to help in 11 of 13 studies with measurable effects — the evidence leans clearly favourable.
Most evidence is from high-quality meta-analyses and randomised trials published 1990–2026 with a typical study size of 168 participants.
Based on 260 studies · 37 meta-analyses · 148 RCTs · 13,917 total participants
Confidence
High confidence
What the studies found
11helped1unclear1didn't help· 247 more without graded effect data
By outcome
Energy & fatigueReduced fatigue and improved vitality · 2-4 weeks
Likely helps178 studies
Therapeutic & clinical
Likely helps41 studies
Cognitive functionGinsenosides enhance cognitive function and working memory · 4-8 weeks
Mostly mechanism / observational25 studies
Glucose & metabolic
Likely helps22 studies
Heart & blood pressure
Mostly mechanism / observational13 studies
Women's health
Mostly mechanism / observational13 studies
Men's vitalityErectile function and libido support · 4-8 weeks
Mostly mechanism / observational10 studies
Endurance & exercise performanceAdaptogenic support improves exercise capacity and VO2max · 4-8 weeks · Modest improvements in endurance and fatigue resistance · 4-8 weeks
102 studies in the last 5 years · Latest meta-analysis: 2025
199020082026
1BODE IndexSystematic ReviewCited 27×n=1,834 · large study2014
These issues should be addressed in future trials.
Chen X et al. · PloS one (2014)
Noticeable benefit
← WorseNo effectBetter →
The main meta-analysis results showed relative benefits for BODE Index in nine studies (mean difference [MD] -0.71, 95% confidence interval [CI] -0.94, -0.47) and 6MWT/D in 17 studies (MD 54.61 meters, 95%CI 33.30, 75.92) in favour of the CHM plus RP groups.
Detailed sub-group and sensitivity analyses were conducted.
Clinically meaningful benefits for BODE Index and 6MWT were found in multiple studies.
The data from the meta-analysis showed that plant adaptogens could provide a number of benefits in the treatment of chronic fatigue, cognitive impairment, and immune protection.
Todorova V et al. · Nutrients (2021)
Extracts from Panax ginseng, Eleutherococcus senticosus, Rhaponticum carthamoides, Rhodiola rosea, and Schisandra chinensis are considered to be naturally occurring adaptogens and, in particular, plant adaptogens.
About 50 years ago, plant adaptogens were first used in professional sports due to their high potential to increase the body's resistance to stress and to improve physical endurance.
Although now many people take plant adaptogens, the clinical trials on human are limited.
3Chemotherapy-induced nausea and vomiting (CINV)Meta-AnalysisCited 40×n=1,843 · large study2016
The oxaliplatin plus TM groups showed significantly reduced CINV (risk ratio 0.65 [0.59, 0.71], I(2) = 28%) compared with oxaliplatin controls, with or without the addition of conventional anti-eme...
Chen MH et al. · Phytotherapy research : PTR (2016)
Large benefit
← WorseNo effectBetter →
The oxaliplatin plus TM groups showed significantly reduced CINV (risk ratio 0.65 [0.59, 0.71], I(2) = 28%) compared with oxaliplatin controls, with or without the addition of conventional anti-emetics.
These plants warrant further clinical research as potential additions to chemotherapy regimens in patients whose CINV is not sufficiently well controlled by conventional therapies.
4Sexual arousalMeta-AnalysisCited 2×n=536 · large study2021
Preliminary evidence suggests that Tribulus terrestris and Panax ginseng may be effective as alternative treatments for FSD in a clinical setting.
Sha'ari N et al. · Phytomedicine : international journal of phytotherapy and phytopharmacology (2021)
Large benefit
← WorseNo effectBetter →
Likely real
Panax ginseng was found to be effective in treating sexual arousal (SMD = 0.54, 95% CI = 0.11 - 0.97, p = 0.014) and sexual desire (SMD = 0.59, 95% CI = 0.27 - 0.90, p < 0.001) compared to placebo.
Preliminary evidence suggests that Tribulus terrestris and Panax ginseng may be effective as alternative treatments for FSD in a clinical setting.