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Pgn6.0
Panax Ginseng Research
Likely helps
263 peer-reviewed studies
What the evidence says
Too few graded studies
Panax Ginseng doesn't have enough studies with structured effect-size data yet to pool a verdict. Browse the studies below for individual findings.
Most evidence is from high-quality meta-analyses and randomised trials published 1990–2026 with a typical study size of 129 participants.
Based on 263 studies · 32 meta-analyses · 139 RCTs · 4,162 total participants
Confidence
High confidence
What the studies found
2helped· 261 more without graded effect data
By outcome
Energy & fatigueReduced fatigue and improved vitality · 2-4 weeks
Too few graded studies179 studies
Therapeutic & clinical
Too few graded studies39 studies
Cognitive functionNo convincing memory benefit in healthy people (Cochrane 21154383) · 4-8 weeks
Too few graded studies25 studies
Glucose & metabolic
Too few graded studies21 studies
Women's health
Too few graded studies14 studies
Heart & blood pressure
Too few graded studies12 studies
Men's vitalityErectile function and libido support · 4-8 weeks
Too few graded studies11 studies
Safety profile
Too few graded studies10 studies
Endurance & exercise performanceAdaptogenic support improves exercise capacity and VO2max · 4-8 weeks · Modest improvements in endurance and fatigue resistance · 4-8 weeks
Immune supportGinsenosides raise NK-cell activity in laboratory studies. No cited trial measured immune function or infections · 4-8 weeks
Too few graded studies2 studies
Inflammation
Too few graded studies1 study
By the numbers
Pulled from 34 studies with measurable effects
Likely real effects
100%
across studies
People studied
4,162
typical study: 129 people
Strongest designs
171
32 pooled, 139 randomised
Showed benefit
100%
2/2 studies
How long studies ran
1–4 weeks
2
3+ months
1
Populations Studied
Healthy adults2
Women with female sexual dysfunction1
Stable COPD patients1
Colorectal cancer patients receiving oxaliplatin-based chemotherapy1
Active research area
109 studies in the last 5 years · Latest meta-analysis: 2025
199020082026
1Sexual arousalMeta-AnalysisCited 2×2021
In plain English: Preliminary evidence suggests that Tribulus terrestris and Panax ginseng may be effective as alternative treatments for FSD in a clinical setting.
Sha'ari N et al. · Phytomedicine : international journal of phytotherapy and phytopharmacology (2021)
Large benefit
← WorseNo effectBetter →
Likely real
A total of 536 studies were identified, with 20 of them meeting the criteria.
Panax ginseng was found to be effective in treating sexual arousal (SMD = 0.54, 95% CI = 0.11 - 0.97, p = 0.014) and sexual desire (SMD = 0.59, 95% CI = 0.27 - 0.90, p < 0.001) compared to placebo.
Other natural products reviewed in this study, such as Trifolium pretense, did not differ significantly from placebo in terms of improving FSD.
2BODE indexSystematic ReviewCited 27×n=1,834 · large study2014
In plain English: These issues should be addressed in future trials.
Chen X et al. · PloS one (2014)
The main meta-analysis results showed relative benefits for BODE Index in nine studies (mean difference [MD] -0.71, 95% confidence interval [CI] -0.94, -0.47) and 6MWT/D in 17 studies (MD 54.61 meters, 95%CI 33.30, 75.92) in favour of the CHM plus RP groups.
Detailed sub-group and sensitivity analyses were conducted.
Clinically meaningful benefits for BODE Index and 6MWT were found in multiple studies.
3Chemotherapy-induced nausea and vomiting (CINV)Meta-AnalysisCited 45×n=1,843 · large study2016
In plain English: The oxaliplatin plus TM groups showed significantly reduced CINV (risk ratio 0.65 [0.59, 0.71], I(2) = 28%) compared with oxaliplatin controls, with or without the addition of conventional anti-eme...
Chen MH et al. · Phytotherapy research : PTR (2016)
The oxaliplatin plus TM groups showed significantly reduced CINV (risk ratio 0.65 [0.59, 0.71], I(2) = 28%) compared with oxaliplatin controls, with or without the addition of conventional anti-emetics.
These plants warrant further clinical research as potential additions to chemotherapy regimens in patients whose CINV is not sufficiently well controlled by conventional therapies.
16Antiaging mechanisms of dietary saponinsSystematic ReviewCited 4×2025
In plain English: Future antiaging research on dietary saponins should prioritize high-purity monomers, optimize their bioactive structure, and yield via synthetic biology and nanoencapsulation, followed by clinical validation of efficacy.
Guo C et al. · Journal of agricultural and food chemistry (2025)
Dietary saponins can achieve antiaging effects through antioxidant, anti-inflammatory, metabolism promotion, skin protection, neuroprotection and other mechanisms. The review covers saponins from several plants, Panax ginseng among them.
Moreover, some antiaging products based on dietary saponins have been developed and utilized as functional foods or nutritional supplements to achieve antiaging in human wellness.
This review systematically reviews antiaging mechanisms of dietary saponins, including their structure-activity relationship, from fundamental research to the development of associated products.