PHGG – Forschung

Impact of the H3K27M mutation on survival in pediatric high-grade glioma: a systematic review and meta-analysis.

Lu VM, Alvi MA, McDonald KL, Daniels DJ · J Neurosurg Pediatr (2019)

Extent of Tumor Resection and Survival in Pediatric Patients With High-Grade Gliomas: A Systematic Review and Meta-analysis.

Hatoum R, Chen JS, Lavergne P, Shlobin NA, Wang A, Elkaim LM · JAMA Netw Open (2022)

A systematic study of molecular diagnosis, treatment, and prognosis in infant-type hemispheric glioma: An individual patient data meta-analysis of 164 patients.

Chavaz L, Bagchi A, Dhanda SK, Toutain F, Pfister SM, Sturm D · Neuro Oncol (2026)

Role of PHGG as a dietary fiber: a review article

Einfach gesagt: Not all the fibers are the same: this is a fact.

Quartarone G · Minerva gastroenterologica e dietologica (2013)

Role of guar fiber in appetite control

Einfach gesagt: Regular intake of guar fiber at a dose of 2g/serving provided significant sustained post-meal satiation effects and minimized the inter-meal calorie intake by about 20% in normal subjects.

Rao TP · Physiology & behavior (2016)

[Clinical utility of partially hydrolyzed guar gum: review of evidence and experience]

Einfach gesagt: In other clinical situations, more quality studies would be necessary in order to make concrete recommendations.

Cantón Blanco A et al. · Nutricion hospitalaria (2017)

The effect of fiber supplementation on the prevention of diarrhea in hospitalized patients receiving enteral nutrition: A meta-analysis of randomized controlled trials with the GRADE assessment.

Kaewdech A, Sripongpun P, Wetwittayakhlang P, Churuangsuk C · Front Nutr (2022)

Probiotics for Irritable Bowel Syndrome: Clinical Data in Children.

Giannetti E, Staiano A · J Pediatr Gastroenterol Nutr (2016)

Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndrome

Einfach gesagt: Moreover, PHGG seems to have prebiotic properties because it increases the colonic contents of short-chain fatty acids, Lactobacilli, and Bifidobacteria.

Giannini EG et al. · Nutrition (Burbank, Los Angeles County, Calif.) (2006)

Continuous partially hydrolyzed guar gum intake reduces cold-like symptoms: a randomized, placebo-controlled, double-blinded trial in healthy adults

Einfach gesagt: PHGG intake may affect immune function and suppress cold-like symptoms through the production of SCFAs in healthy adults.

Sakai S et al. · European review for medical and pharmacological sciences (2022)

Maintenance therapy with partially hydrolyzed guar gum in the conservative treatment of chronic anal fissure: results of a prospective, randomized study.

Brillantino A, Iacobellis F, Izzo G, Di Martino N, Grassi R, Renzi A · Biomed Res Int (2014)

Continuous partially hydrolyzed guar gum intake reduces cold-like symptoms: a randomized, placebo-controlled, double-blinded trial in healthy adults.

Sakai S, Kamada Y, Takano H, Ichikawa M, Kurimoto M, Katsuyama HK · Eur Rev Med Pharmacol Sci (2022)

High-fiber diet supplementation in patients with irritable bowel syndrome (IBS): a multicenter, randomized, open trial comparison between wheat bran diet and partially hydrolyzed guar gum (PHGG).

Parisi GC, Zilli M, Miani MP, Carrara M, Bottona E, Verdianelli G · Dig Dis Sci (2002)

Reduction in diarrhea incidence by soluble fiber in patients receiving total or supplemental enteral nutrition.

Homann HH, Kemen M, Fuessenich C, Senkal M, Zumtobel V · JPEN J Parenter Enteral Nutr (1994)

Can partially hydrolyzed guar gum be an alternative to lactulose in treatment of childhood constipation?

Üstündağ G, Kuloğlu Z, Kirbaş N, Kansu A · Turk J Gastroenterol (2010)

Treatment effects of partially hydrolyzed guar gum on symptoms and quality of life of patients with irritable bowel syndrome. A multicenter randomized open trial.

Parisi G, Bottona E, Carrara M, Cardin F, Faedo A, Goldin D · Dig Dis Sci (2005)

Efficacy of partially hydrolyzed guar gum (PHGG) supplemented modified oral rehydration solution in the treatment of severely malnourished children with watery diarrhoea: a randomised double-blind controlled trial.

Alam NH, Ashraf H, Kamruzzaman M, Ahmed T, Islam S, Olesen MK · J Health Popul Nutr (2015)

The Short-Term Effects and Tolerability of Low-Viscosity Soluble Fibre on Gastroparesis Patients: A Pilot Clinical Intervention Study.

Suresh H, Zhou J, Ho V · Nutrients (2021)

Improvement of the metabolic syndrome profile by soluble fibre - guar gum - in patients with type 2 diabetes: a randomised clinical trial.

Dall'Alba V, Silva FM, Antonio JP, Steemburgo T, Royer CP, Almeida JC · Br J Nutr (2013)

Effectiveness of Partially Hydrolyzed Guar Gum on Cognitive Function and Sleep Efficiency in Healthy Elderly Subjects in a Randomized, Double-Blind, Placebo-Controlled, and Parallel-Group Study.

Abe A, Kapoor MP, Morishima S, Ozeki M, Sato N, Takara T · Nutrients (2024)