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Pg6.0
PHGG Research
Likely helps
41 peer-reviewed studies
What the evidence says
Likely helps
PHGG appears to help in 5 of 5 studies with measurable effects — the evidence leans clearly favourable.
Most evidence is from high-quality meta-analyses and randomised trials published 1994–2026 with a typical study size of 52 participants.
Based on 41 studies · 3 meta-analyses · 30 RCTs · 896 total participants
Confidence
High confidence
What the studies found
5helped· 36 more without graded effect data
By outcome
Digestive healthImproved bowel regularity and reduced IBS symptoms within 2-4 weeks · 2-4 weeks
Likely helps35 studies
Safety profile
Mostly mechanism / observational5 studies
Weight management
Mostly mechanism / observational4 studies
Therapeutic & clinical
Mostly mechanism / observational4 studies
Glucose & metabolic
Too few graded studies2 studies
Immune support
Too few graded studies2 studies
Cognitive function
Too few graded studies2 studies
Sleep & insomnia
Too few graded studies2 studies
By the numbers
Pulled from 18 studies with measurable effects
Likely real effects
75%
across studies
People studied
896
typical study: 52 people
Strongest designs
33
3 pooled, 30 randomised
Showed benefit
100%
5/5 studies
How long studies ran
Under a week
3
1–3 months
4
3+ months
1
Populations Studied
Patients with irritable bowel syndrome2
Healthy adults2
Healthy subjects2
Normal subjects1
Active research area
15 studies in the last 5 years · Latest meta-analysis: 2026
199420102026
1Meta-Analysis2026
Chavaz L, Bagchi A, Dhanda SK, Toutain F, Pfister SM, Sturm D · Neuro Oncol (2026)
In other clinical situations, more quality studies would be necessary in order to make concrete recommendations.
Cantón Blanco A et al. · Nutricion hospitalaria (2017)
Its use in enteral nutrition associated diarrhea is supported by several studies and by the recommendations of scientific societies such as the European Society for Clinical Nutrition and Metabolism and the American Society for Parenteral and Enteral Nutrition.
The usefulness of GGPH has been studied in many other clinical situations, such as diabetes, hypercholesterolemia, bacterial overgrowth, etc. with promising results.
Conclusions: GGPH is useful in the management of enteral nutrition associated diarrhea.
Regular intake of guar fiber at a dose of 2g/serving provided significant sustained post-meal satiation effects and minimized the inter-meal calorie intake by about 20% in normal subjects.
Rao TP · Physiology & behavior (2016)
Large benefit
← WorseNo effectBetter →
Regular intake of guar fiber at a dose of 2g/serving provided significant sustained post-meal satiation effects and minimized the inter-meal calorie intake by about 20% in normal subjects.
Guar fiber containing >85% dietary fiber, with clear solubility and negligible taste impact, may be an ideal natural dietary fiber for use in food and supplement applications at low dosage levels for appetite control.
The intake of guar fiber alone at a dose >5g/serving or its combination with protein (2.6g guar fiber+8g protein/serving) showed acute satiety effects in normal subjects.
6Safety and efficacy reviewSystematic ReviewCited 12×2013
Not all the fibers are the same: this is a fact.
Quartarone G · Minerva gastroenterologica e dietologica (2013)
Not all the fibers are the same: this is a fact.
Promoting the specific knowledge of their characteristics is very important if healthcare professionals want to give their patients the best options for functional gastrointestinal disorders or nutritional needs.
PHGG (Benefiber™ Novartis CH) has been proved to be safe and effective in promoting gut health.
7Systematic Review2022
Kaewdech A, Sripongpun P, Wetwittayakhlang P, Churuangsuk C · Front Nutr (2022)
Moreover, PHGG seems to have prebiotic properties because it increases the colonic contents of short-chain fatty acids, Lactobacilli, and Bifidobacteria.
Giannini EG et al. · Nutrition (Burbank, Los Angeles County, Calif.) (2006)
Partially hydrolyzed guar gum (PHGG) is a water-soluble, non-gelling fiber that has provided therapeutic benefits.
In clinical trials, PHGG decreased symptoms in constipation-predominant and diarrhea-predominant forms of IBS and decreased abdominal pain.
Further, an improvement in quality of life was observed in patients with IBS during and after treatment with PHGG.
In summary, supplementation with PHGG was effective in improving cognitive functions, particularly visual memory, as well as enhancing sleep quality and vitality in healthy elderly individuals (UMIN000049070).
Abe A et al. · Nutrients (2024)
The visual memory scores in cognitive function tests and sleepiness on rising scores related to sleep quality were significantly improved in the PHGG group compared to the placebo group.
Vigor-activity scores were significantly improved, while the scores for Confusion-Bewilderment decreased significantly in the PHGG group when compared to the baseline.
No significant differences were observed in mood parameters between the groups.