Higgins JP, Flicker L · Cochrane Database Syst Rev (2003)
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58 peer-reviewed studies
What the evidence says
Most Phosphatidylcholine studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 1979–2026 with a typical study size of 100 participants.
Based on 58 studies · 1 meta-analysis · 55 RCTs · 7,680 total participants
Confidence
High confidenceBy outcome
7 studies in the last 5 years · Latest meta-analysis: 2003
Higgins JP, Flicker L · Cochrane Database Syst Rev (2003)
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Chan PC, Tam SC, Robinson JD, Yu L, Ip MS, Chan CY · Nephron (1991)
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Zeman M, Zák A, Stolba P · Sb Lek (1995)
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Holan KR, Holzbach RT, Hsieh JY, Welch DK, Turcotte JG · Digestion (1979)
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Pérez-Cruet J, Menéndez I, Alvarez-Ghersi J, Falcón JR, Valderrábano O, Castro-Urrutia EC · Bol Asoc Med P R (1981)
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Su HL, Zhu YX, Gao ZJ, Dong XY, Zhu JY, Lei WR · Zhonghua Gan Zang Bing Za Zhi (2011)
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Ozerova IN, Akhmedzhanov NM, Perova NV, Paramonova IV · Bull Exp Biol Med (2005)
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Lieber CS, Weiss DG, Groszmann R, Paronetto F, Schenker S · Alcohol Clin Exp Res (2003)
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Jenkins PJ, Portmann BP, Eddleston AL, Williams R · Liver (1982)
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Brinkman SD, Pomara N, Goodnick PJ, Barnett N, Domino EF · J Clin Psychopharmacol (1982)
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Gelenberg AJ, Dorer DJ, Wojcik JD, Falk WE, Brotman AW, Leahy L · J Clin Psychiatry (1990)
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Guan R, Ho KY, Kang JY, Yap I, Gwee KA, Tan CC · Aliment Pharmacol Ther (1995)
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Buchman AL, Dubin M, Jenden D, Moukarzel A, Roch MH, Rice K · Gastroenterology (1992)
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Ma AL, Guo XZ, Liu X, Xu Q, Wang TL · Zhonghua Gan Zang Bing Za Zhi (2011)
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Hirose A, Terauchi M, Osaka Y, Akiyoshi M, Kato K, Miyasaka N · Nutr J (2018)
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Volz HP, Hehnke U, Hauke W · MMW Fortschr Med (2004)
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Kozlova IV, Myalina YN, Lipina LP, Bakulev AL · Ter Arkh (2017)
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Cheatham CL, Goldman BD, Fischer LM, da Costa KA, Reznick JS, Zeisel SH · Am J Clin Nutr (2012)
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Visco G · Clin Ter (1985)
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Kirsten R, Heintz B, Nelson K, Hesse K, Schneider E, Oremek G · Int J Clin Pharmacol Ther (1994)
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