In a randomized, double-blind, placebo-controlled trial in acute viral hepatitis, Picrorhiza root powder shortened the time for bilirubin to normalize (27 vs 76 days) — a small but genuine human signal.
Vaidya AB et al. · J Postgrad Med (1996)
- Randomized, double-blind, placebo-controlled trial in acute viral hepatitis (HBsAg-negative): Pk 375mg three times daily for 2 weeks (n=15) vs placebo (n=18)
- Time for total serum bilirubin to fall to ~2.5 mg% was 27.4 days with Pk vs 75.9 days with placebo
- Differences in bilirubin, SGOT and SGPT were significant vs placebo