1Meta-Analysis2004
Schubert M, Venkataramanan R, Holt DW, Shaw LM, McGhee W, Reyes J · Am J Transplant (2004)
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306 peer-reviewed studies
What the evidence says
Most Rapamycin studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 1999–2026 with a typical study size of 218 participants.
Based on 306 studies · 25 meta-analyses · 255 RCTs · 242 total participants
Confidence
High confidenceBy outcome
Only 28 studies in the last 5 years · Latest meta-analysis: 2024
Schubert M, Venkataramanan R, Holt DW, Shaw LM, McGhee W, Reyes J · Am J Transplant (2004)
Asrani SK, Leise MD, West CP, Murad MH, Pedersen RA, Erwin PJ · Hepatology (2010)
Zhang ZH, Li LX, Li P, Lv SC, Pan B, He Q · J Invest Surg (2019)
Mulay AV, Cockfield S, Stryker R, Fergusson D, Knoll GA · Transplantation (2006)
Wang L, Gu Z, Zhai R, Li D, Zhao S, Luo L · Transfusion (2015)
Liu JY, Song M, Guo M, Huang F, Ma BJ, Zhu L · Am J Ther (2016)
Gao L, Xu F, Cheng H, Liu J · Transplant Proc (2018)
Liu YM, Shao YQ, He Q · Transplant Proc (2014)
Yang A, Wang B · Am J Ther (2015)
Menon KV, Hakeem AR, Heaton ND · Aliment Pharmacol Ther (2013)
Wang Q, Luo M, Xiang B, Chen S, Ji Y · Respir Res (2020)
Knoll GA, Kokolo MB, Mallick R, Beck A, Buenaventura CD, Ducharme R · BMJ (2014)
Hahn D, Hodson EM, Hamiwka LA, Lee VW, Chapman JR, Craig JC · Cochrane Database Syst Rev (2019)
Liang W, Wang D, Ling X, Kao AA, Kong Y, Shang Y · Liver Transpl (2012)
Yanik EL, Siddiqui K, Engels EA · Cancer Med (2015)
Li M, Zhou Y, Chen C, Yang T, Zhou S, Chen S · Orphanet J Rare Dis (2019)
Xue C, Dai B, Mei C · Nephron Clin Pract (2013)
Gu YH, Du JX, Ma ML · Asian Pac J Cancer Prev (2012)
Oberbauer R · Ther Drug Monit (2005)
Webster AC, Lee VW, Chapman JR, Craig JC · Transplantation (2006)