Sayehmiri K, Shohani M, Qavam S, Tavan H · Life Sci (2025)
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220 peer-reviewed studies
What the evidence says
Most Rosuvastatin (Crestor) studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 2006–2026 with a typical study size of 1,039 participants.
Based on 220 studies · 24 meta-analyses · 193 RCTs · 111,472 total participants
Confidence
High confidenceBy outcome
39 studies in the last 5 years · Latest meta-analysis: 2026
Sayehmiri K, Shohani M, Qavam S, Tavan H · Life Sci (2025)
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Sridharan K, Sivaramakrishnan G · Eur J Intern Med (2017)
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You T, Liu XG, Hou XD, Wang XK, Xie HH, Ding F · Clin Exp Hypertens (2017)
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Ma Q, Zhou Y, Zhai G, Gao F, Zhang L, Wang J · Angiology (2016)
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Zarei R, Vatankhah P, Chaparzade S, Ebrahimirad F, Hassani P, Khamisi N · Am J Dent (2026)
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Lee S, Yang S, Chang MJ · PLoS One (2021)
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Qian C, Wei B, Ding J, Wu H, Cai X, Li B · Am J Cardiol (2015)
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Kumar A, Shariff M, Doshi R · Eur J Prev Cardiol (2020)
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Zhou X, Dai J, Xu X, Wang Z, Xu H, Chen J · Angiology (2019)
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Karlson BW, Nicholls SJ, Lundman P, Barter PJ, Palmer MK · Cardiology (2018)
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Liang M, Yang S, Fu N · Medicine (Baltimore) (2017)
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Pan Y, Tan Y, Li B, Li X · Lipids Health Dis (2015)
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Karlson BW, Palmer MK, Nicholls SJ, Barter PJ, Lundman P · Atherosclerosis (2017)
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Borovac JA, Leth-Olsen M, Kumric M, D'Amario D, Schwarz K, Glavas D · Eur J Clin Pharmacol (2022)
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Ye Z, Lu H, Su Q, Guo W, Dai W, Li H · PLoS One (2017)
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Zhang J, Guo Y, Jin Q, Bian L, Lin P · Drug Des Devel Ther (2018)
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Martí-Carvajal AJ, Kwong JS · Cochrane Database Syst Rev (2016)
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Omayer A, Mohamed MI, Shahid M, Hoque SMH, Mohamed NEAM, Elsayed EMA · BMC Cardiovasc Disord (2026)
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Singh H, Kaur S, Kaushal P, Sharma J, Singla M · Expert Rev Clin Pharmacol (2024)
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Karlson BW, Palmer MK, Nicholls SJ, Lundman P, Barter PJ · Eur J Prev Cardiol (2016)
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