We use essential cookies (authentication, your saved goals/stack) by default. With your permission we'll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more
Shj8.0
Shilajit Research
Mostly mechanism / observationalModerate safety
21 peer-reviewed studies
What the evidence says
Mostly mechanism / observational
Most Shilajit studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality randomised trials published 2007–2025 with a typical study size of 63 participants.
Based on 21 studies · 12 RCTs · 804 total participants
Confidence
Moderate
What the studies found
2helped· 19 more without graded effect data
By outcome
Energy & fatigueImproved energy and reduced fatigue · 2-4 weeks
Mostly mechanism / observational5 studies
Safety profile
Mostly mechanism / observational5 studies
Men's vitalityIncreases total and free testosterone in clinical trials · 8-12 weeks · Total testosterone and sperm quality improvements · 4-12 weeks
Mostly mechanism / observational4 studies
Therapeutic & clinical
Mostly mechanism / observational4 studies
Bone healthSupports bone mineral density and skeletal strength · 8-12 weeks
Hussain A et al. · Biological trace element research (2024)
The levels of reported metals in Shilajit were found to be lower than the permissible limits set by WHO and FDA, except in few studies where exceeded levels were reported.
Shilajit consumption without knowing permissible levels of metals is not safe and could pose serious health problems.
Although the humic substances and few metals in Shilajit are beneficial in terms of chelating toxic heavy metals, the data on metal detoxification still needs to be clarified.
We emphasize the relevance of nutraceuticals as a main actor in the prevention and/or control of dementia and particularly AD.
Maccioni RB et al. · Biomolecules (2022)
Based on markers data, early preventive interventions could reduce more than 40% of AD cases.
Anti-inflammatory agents with anti-aggregation properties that help to control cognitive impairment, include quercetin, biocurcumin, rosemarinic acid, and Andean shilajit.
Anthocyanidins, e.g., delphinidin, malvidin, and natural flavonoids, are also included.
Additional well-controlled human and animal studies involving the use of standardized products are needed.
Stohs SJ · Phytotherapy research : PTR (2014)
Furthermore, animal and human data support its use as a 'revitalizer', enhancing physical performance and relieving fatigue with enhanced production of ATP.
Key constituents in shilajit responsible for these effects appear to be dibenzo-α-pyrones and fulvic acid and their derivatives.
Various mechanistic studies provide support for the above observed effects.
This integrated view on nutraceutical opens a new pathway for future investigations and clinical trials that are likely to render some results based on medical evidence.
Calfio C et al. · Journal of Alzheimer's disease : JAD (2020)
In addition, we also discuss the activity of nutraceutical compounds and phytopharmaceuticals formulae, mainly directed to tau protein aggregates mechanisms of action.
These include compounds such as curcumin, resveratrol, epigallocatechin-3-gallate, morin, delphinidins, quercetin, luteolin, oleocanthal, and meganatural-az and other phytochemicals such as huperzine A, limonoids, azaphilones, and aged garlic extract.
Finally, we revise the nutraceutical formulae BrainUp-10 composed of Andean shilajit and B-complex vitamins, with memory enhancement activity and the control of neuropsychiatric distress in AD patients.
We analyze the status of biological studies and present data of a clinical trial developed in patients with mild AD.
Carrasco-Gallardo C et al. · Archives of medical research (2012)
We analyze the status of biological studies and present data of a clinical trial developed in patients with mild AD.
Studies suggest that shilajit and its active principle fulvic acid, as well as a formula of shilajit with B complex vitamins, emerge as novel nutraceutical with potential uses against this brain disorder.
Based on the earlier studies, the bioactivity of shilajit lacks substantial evidence.
Wilson E et al. · Journal of ethnopharmacology (2011)
Based on the earlier studies, the bioactivity of shilajit lacks substantial evidence.
Nevertheless, further studies are imperative to overcome the lacuna in establishing the antioxidant property of shilajit and more specific assays are needed to vouch shilajit as an immuno-modulator which may be of use to establish its rasayana potential.
Shilajit has been attributed with many miraculous healing properties.
Agarwal SP et al. · Phytotherapy research : PTR (2007)
It has been found to consist of a complex mixture of organic humic substances and plant and microbial metabolites occurring in the rock rhizospheres of its natural habitat.
Shilajit has been used as a rejuvenator and an adaptogen for thousands of years, in one form or another, as part of traditional systems of medicine in a number of countries.
Many therapeutic properties have been ascribed to it, a number of which have been verified by modern scientific evaluation.
Methods: In total, 166 sedentary men and women with at least two markers of metabolic syndrome participated in a randomized, placebo-controlled, parallel-arm, and repeated-measure intervention study, of which 109 completed the study (48.6 ± 10 yrs., 34.2 ± 6 kg/m2, 41.3 ± 7% fat).
Data were obtained at 0, 6, and 12 weeks of supplementation, and analyzed using general linear model multivariate and univariate analyses with repeated measures, pairwise comparisons, and mean changes from the baseline with 95% confidence intervals (CIs).
Differences among groups were more consistently seen at 6 weeks rather than 12 weeks.
12Tibial bone union healing timeRCTCited 10×n=160 · medium study2020
Conclusions: The current study showed that oral consumption of momiai after tibial shaft fracture surgery could be a promising option to reduce the healing time.
Sadeghi SMH et al. · Journal of alternative and complementary medicine (New York, N.Y.) (2020)
Noticeable benefit
← WorseNo effectBetter →
Likely real
There was no significant difference between groups in terms of demographic and descriptive data.
At the end of the study, the mean time of tibial bone union was 129 days in the experimental group, while it was 153 days in the placebo group (p < 0.049).
There was no significant difference in the reported adverse effects between the two groups (p = 0.839).
13Bone mineral density preservationRCTCited 22×n=60 · small study2022
Daily supplementation with this shilajit extract supports BMD in postmenopausal women with osteopenia in part by attenuating the increased bone turnover, inflammation and oxidative stress that coincides with estrogen deficiency in this population at increased risk for osteoporosis and bone fractures.
Pingali U et al. · Phytomedicine : international journal of phytotherapy and phytopharmacology (2022)
Likely real
CTX-1, BALP, and RANKL decreased, whereas OPG increased, in both groups supplemented with the shilajit extract, but not in the placebo group, resulting in significantly decreased or increased percentage changes from baseline, respectively.
MDA was significantly decreased (p < 0.001) and GSH was significantly increased (p < 0.001) in both supplemented groups compared to placebo from week 12 for the duration of the study.
Progressive reductions in hsCRP were observed in both supplemented groups, resulting in significantly decreased percentage changes from baseline in supplemented women compared to placebo (p < 0.001).
In conclusion, 8 weeks of Shilajit supplementation with 500 and 1000 mg·d-1 increased type 1 collagen synthesis as indicated by serum levels of pro-c1α1.
Neltner TJ et al. · Journal of dietary supplements (2024)
Individual subject responses were assessed using the minimal clinically important difference and Chi-squared tests.
In conclusion, 8 weeks of Shilajit supplementation with 500 and 1000 mg·d-1 increased type 1 collagen synthesis as indicated by serum levels of pro-c1α1.
16Muscular strength retention and serum hydroxyproline levelsRCTCited 9×n=63 · small study2019
The results of the present study demonstrated that 8 weeks of PrimaVie® Shilajit supplementation at 500 mg·d- 1 promoted the retention of maximal muscular strength following the fatiguing protocol and decreased baseline HYP.
Keller JL et al. · Journal of the International Society of Sports Nutrition (2019)
The results of the present study demonstrated that 8 weeks of PrimaVie® Shilajit supplementation at 500 mg·d- 1 promoted the retention of maximal muscular strength following the fatiguing protocol and decreased baseline HYP.
Thus, PrimaVie® Shilajit supplementation at 500 mg·d- 1 elicited favorable muscle and connective tissue adaptations.
Das A et al. · Journal of the American College of Nutrition (2019)
At a higher dose (250 mg bid), shilajit improved skin perfusion when compared to baseline or the placebo.
Pathway analysis identified shilajit-inducible genes relevant to endothelial cell migration, growth of blood vessels, and ECM which were validated by quantitative real-time polymerase chain reaction (RT-PCR) analysis.
The study provided maiden evidence that oral Shilajit supplementation in adult overweight/class I obese human subjects promoted skeletal muscle adaptation through upregulation of ECM-related genes that control muscle mechanotransduction properties, elasticity, repair, and regeneration.