1Meta-Analysis2020
Hao Y, Zhu Y, Mao Y, Xu J, He X, Huang S · Life Sci (2020)
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182 peer-reviewed studies
What the evidence says
Most Sildenafil (Viagra) studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 1998–2026.
Based on 178 studies · 22 meta-analyses · 142 RCTs
Confidence
High confidenceBy outcome
50 studies in the last 5 years · Latest meta-analysis: 2025
Hao Y, Zhu Y, Mao Y, Xu J, He X, Huang S · Life Sci (2020)
Usmani SUR, Hasan SU, Ali SH, Ahmed SH, Pervez N, Danial M · Asian J Surg (2024)
García-Perdomo HA, Echeverría-García F, Tobías A · Urol Int (2017)
Qiu S, Tang Z, Deng L, Liu L, Han P, Yang L · Sci Rep (2016)
Kelly LE, Ohlsson A, Shah PS · Cochrane Database Syst Rev (2017)
Liu LY, Sun T, Liu Y, Sun YY, Ma FZ · Nephron (2019)
Luo K, Tang J, Chen H, Zhang X, Wang H · Pediatr Pulmonol (2024)
Fei Q, Pan J, Zhang F, Lin Y, Yuan T · Crit Care Med (2024)
Hirata K, Nakahari A, Takeoka M, Watanabe M, Nishimura Y, Katayama Y · Pediatr Int (2024)
Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T · Int Urol Nephrol (2017)
Ohl DA, Stecher V, Tseng LJ · Int J Clin Pract (2017)
Jiang R, Wang L, Zhu CT, Yuan P, Pudasaini B, Zhao QH · Hypertens Res (2015)
Ferreira RDDS, Negrini R, Bernardo WM, Simões R, Piato S · PLoS One (2019)
Zhuo ML, Xu JL, Zhang W, Rao GW, Zheng Q · Pathol Res Pract (2025)
Paauw ND, Terstappen F, Ganzevoort W, Joles JA, Gremmels H, Lely AT · Hypertension (2017)
Kaminetsky JC, Stecher V, Tseng LJ · Int J Clin Pract (2017)
Khouri C, Lepelley M, Roustit M, Montastruc F, Humbert M, Cracowski JL · Chest (2018)
Manouchehri E, Makvandi S, Razi M, Sahebari M, Larki M · BMC Pediatr (2024)
Jiang L, Sun W, Zhang K, Zhou B, Kong X · Int Heart J (2018)
Chen Y, Li F, Luo J, Chen J, Luo P, Li J · Can Respir J (2021)