1Meta-Analysis1998
Cunliffe WJ, Poncet M, Loesche C, Verschoore M · Br J Dermatol (1998)
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390 peer-reviewed studies
What the evidence says
Most Tretinoin (Retin-A) studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 1975–2026.
Based on 390 studies · 18 meta-analyses · 362 RCTs
Confidence
High confidenceBy outcome
Only 29 studies in the last 5 years · Latest meta-analysis: 2026
Cunliffe WJ, Poncet M, Loesche C, Verschoore M · Br J Dermatol (1998)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Chen L, Wang J, Hu X, Xu X · Hematology (2014)
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Bellos F, Mahlknecht U · Onkologie (2008)
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Küley-Bagheri Y, Kreuzer KA, Monsef I, Lübbert M, Skoetz N · Cochrane Database Syst Rev (2018)
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Nighland M, Grossman R · J Drugs Dermatol (2008)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Falker-Gieske C, Mott A, Franzenburg S, Tetens J · BMC Genomics (2021)
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Ahmad H, Henna F, Khurram S, Khan A, Ahmed A, Ali MH · BMC Cancer (2026)
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Wang H, Chen XY, Wang BS, Rong ZX, Qi H, Chen HZ · Leuk Res (2011)
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Lu H, Guo J, Hong X, Chen A, Zhang X, Shen S · Medicine (Baltimore) (2020)
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Huang RS, Mihalache A, Kuriyan AE, Miranda RN, Felfeli T · Retina (2026)
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Armstrong AW, Cheeney S, Wu J, Harskamp CT, Schupp CW · Am J Clin Dermatol (2012)
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Ma H, Yang J · Acta Haematol (2015)
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Pak K, Shin S, Kim SJ, Kim IJ, Chang S, Koo P · Oncol Res Treat (2018)
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Ma Y, Liu L, Jin J, Lou Y · PLoS One (2016)
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Xu SN, Chen JP, Liu JP, Xia Y · Zhong Xi Yi Jie He Xue Bao (2009)
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Thorne EG, Lufrano L, Boateng F, Sampson AR · Br J Dermatol (1996)
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Verma V, Giri S, Manandhar S, Pathak R, Bhatt VR · Leuk Lymphoma (2016)
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Langdon K, Cosentino S, Wawryk O · Cancer Rep (Hoboken) (2024)
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Margiana R, Pakpahan C, Pangestu M · F1000Res (2022)
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Peinemann F, van Dalen EC, Enk H, Berthold F · Cochrane Database Syst Rev (2017)
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