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5 peer-reviewed studies
What the evidence says
Most Triphala studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from medium-quality randomised trials published 2005–2022 with a typical study size of 80 participants.
Based on 5 studies · 2 RCTs · 137 total participants
Confidence
LowBy outcome
1 study in the last 5 years
The herbal prebiotic Triphala significantly reduced scalp sebum scores compared to placebo.
Zareie E, Mansouri P, Hosseini H, Sadeghpour O, Shirbeigi L, Hejazi S, Emtiazy M · J Dermatolog Treat (2022)
Triphala is a cornerstone of gastrointestinal and rejuvenative treatment, and its polyphenols modulate the human gut microbiome, promoting beneficial Bifidobacteria and Lactobacillus.
Peterson CT, Denniston K, Chopra D · J Altern Complement Med (2017)
The antimicrobial action of triphala against mutans streptococci closely parallels that of chlorhexidine, without the common side effects and at lower cost.
Srinagesh J, Pushpanjali K · Oral Health Prev Dent (2011)
Triphala is effective in inhibiting the growth of human pancreatic cancer cells in both cellular and in vivo models by inducing apoptosis via p53 and ERK activation.
Shi Y, Sahu RP, Srivastava SK · BMC Cancer (2008)
An animal study found Triphala enhanced the neutrophil avidity index in rats (broader phagocytic effects only in immunized animals).
Srikumar R, Jeya Parthasarathy N, Sheela Devi R · Biol Pharm Bull (2005)