36 peer-reviewed studies · Evidence score: 7/10
Walsh CJ et al. • Journal of lower genital tract disease (2024)
The evidence for treating HPV and cervical dysplasia with CAM is of low quality because of lack of standardized, clinically relevant treatment outcomes, lack of standardization of products, and minimal reporting on adverse and long-term effects.
Pilkington K et al. • The Cochrane database of systematic reviews (2022)
Due to the very low certainty of evidence, we were uncertain about the effect of adjunctive Coriolus (in the form of an extract PSK) on adverse events resulting from conventional chemotherapy for colorectal cancer.
Szelenberger R et al. • Molecules (Basel, Switzerland) (2025)
Presented evidence indicates that fungal polysaccharides possess considerable potential as multifunctional hepatoprotective agents, highlighting the need for further mechanistic insight and clinical validation.
Łysakowska P et al. • Molecules (Basel, Switzerland) (2023)
This review focuses on the properties of selected medicinal mushrooms and their effects on the human organism and presents current knowledge on the possibilities of their use in the production of functional foods.
Gariboldi MB et al. • International journal of molecular sciences (2023)
We also report insights into the relationship between dietary consumption of edible mushrooms and breast cancer risk, and the results of clinical studies and meta-analyses focusing on the effects of fungal extracts on breast cancer patients.
Shahrajabian MH et al. • Current HIV research (2023)
The aim of this review article is to survey and introduce important medicinal plants and herbs that have been used for the treatment of HIV, especially the medicinal plants that are common in traditional Chinese medicine, as research to date is limited, and more evidence is required to confirm TCM,s efficacy.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
Xu J et al. • Nutrients (2022)
In summary, there is a need to continue to explore the use of those extracts and to further validate their safety and efficacy.
Yue GG et al. • Molecules (Basel, Switzerland) (2021)
While immune modulation platforms are being built for relevant studies, a brief account on the research targets and related procedures are given.
Hou YN et al. • Cancer journal (Sudbury, Mass.) (2019)
It is important to familiarize health care professionals about popular supplements, so patients can be informed to make decisions that maximize benefits and minimize risks.
Narayanan S et al. • Current oncology reports (2023)
More trials are needed to explore mushroom use during and after cancer treatment.
Wong JH et al. • Applied microbiology and biotechnology (2020)
Antineoplastic effectiveness in human clinical trials and mechanism of anticancer action have been reported for Antrodia camphorata, Cordyceps sinensis, Coriolus versicolor, Ganoderma lucidum, Grifola frondosa, and Lentinula edodes.
Neuwirthová J et al. • Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti (2020)
Both extracts from Reishi and Coriolus, if used in combination with standard therapy or as an adjuvant single agent, have shown benefits at immune function measures, tumor-related symptoms and performance status of cancer patients.
Dou H et al. • Progress in molecular biology and translational science (2019)
The polysaccharide content in PSP is ~60% and the peptide content in PSP is ~10-30%.
Wong JH et al. • Current medicinal chemistry (2018)
These compounds have the potential of development into anticancer drugs.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
Fritz H et al. • Integrative cancer therapies (2015)
PSK may improve immune function, reduce tumor-associated symptoms, and extend survival in lung cancer patients.
Piotrowski J et al. • Postepy higieny i medycyny doswiadczalnej (Online) (2015)
Because of its unique properties and safety, PSP may become a widely used therapeutic agent in the near future.
Oba K et al. • Cancer Immunology, Immunotherapy (2007)
PSK significantly improved survival in gastric cancer patients.
Eliza WL et al. • Recent patents on inflammation & allergy drug discovery (2012)
This meta-analysis has provided strong evidence that Yun Zhi would have survival benefit in cancer patients, particularly in carcinoma of breast, gastric and colorectal.
Spelman K et al. • Alternative medicine review : a journal of clinical therapeutic (2006)
The in vitro and in vivo research demonstrates that the reviewed botanical medicines modulate the secretion of multiple cytokines.
Sze DM et al. • Hematology. American Society of Hematology. Education Program (2009)
Finally, we conclude by highlighting an herbal formulation PHY906 as a potential adjunct to chemotherapy that might become one of the first US Food and Drug Administration (FDA) approved oral herbal medicines for anti-cancer adjunct treatment.