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Wkb3.0

White Kidney Bean Extract Research

Mostly mechanism / observational

6 peer-reviewed studies

What the evidence says

Mostly mechanism / observational

Most White Kidney Bean Extract studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.

Most evidence is from high-quality meta-analyses and randomised trials published 2007–2026 with a typical study size of 543 participants.

Based on 6 studies · 2 meta-analyses · 4 RCTs · 624 total participants

Confidence

High confidence

By outcome

Weight managementInconsistent; meta-analysis found no significant weight loss vs placebo, though some small trials report modest fat/weight reductions · 4-12 weeks (if any)
Mostly mechanism / observational5 studies
Safety profile
Too few graded studies2 studies
Glucose & metabolicPlausible blunting of post-meal glucose spikes by slowing starch digestion, but human glycemic outcome data are limited · Per-meal (acute)
Too few graded studies1 study

Active research area

2 studies in the last 5 years · Latest meta-analysis: 2026

200720162026

1Meta-Analysisn=543 · large study2026

In plain English: In the future, further large-scale, high-quality, and long-term trials are warranted to confirm its efficacy and clarify its potential role in metabolic health.

Shi N, Wang R, Cao X, Huang Z, Lin F, Xu R, Zhang Q. · Nutrition research (New York, N.Y.) (2026)

We hypothesized that WKBE could significantly improve key anthropometric outcomes in adults with overweight and obese compared with placebo, with acceptable safety.
No significant differences were observed in fasting blood glucose, triglycerides, or random insulin.
No serious adverse events related to WKBE were reported.

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2RCT2013

Spadafranca A, Rinelli S, Riva A, Morazzoni P, Magni P, Bertoli S · Br J Nutr (2013)

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3RCT2007

Celleno L, Tolaini MV, D'Amore A, Perricone NV, Preuss HG · Int J Med Sci (2007)

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4RCTn=81 · small study2024

Jäger R, Abou Sawan S, Purpura M, Grube B, Röske Y, De Costa P, Chong PW. · Scientific reports (2024)

In a dose-dependent manner, Phase 2 significantly reduced body weight, fat mass, BMI, waist, hip and in the WKBE HIGH group thigh circumference.
Phase 2 is an effective and safe supplement aiding weight and fat loss.

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5Meta-Analysis2011

In plain English: The poor quality of the included RCT prevents us from drawing any firm conclusions about the effects of P. vulgaris supplementation on body weight.

Onakpoya I, Aldaas S, Terry R, Ernst E. · Br J Nutr (2011)

Of 11 eligible trials, 6 were included; all had serious methodological flaws
Pooled weight loss was NOT statistically significant versus placebo (MD -1.77 kg, 95% CI -3.33 to 0.33)
A significant body-fat reduction was found (MD -1.86 kg) but with heterogeneity between trials

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6RCT2014

In plain English: At the end of the WL study, the IQP-PV-101 group lost a mean of 2.91 ± 2.63 kg in body weight compared with 0.92 ± 2.00 kg in the placebo group (P < 0.001).

Grube B, Chong WF, Chong PW, Riede L. · Obesity (Silver Spring) (2014)

Double-blind 12-week weight-loss phase plus 24-week open-label maintenance, all on a mildly hypocaloric diet
The extract group lost ~2.91 kg vs ~0.92 kg for placebo (a roughly 2 kg net difference)
No serious or related adverse events over 36 weeks

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View in Research Library

White Kidney Bean Extract Research

Mostly mechanism / observational

White kidney bean extract reduces body weight and adiposity with acceptable safety in adults with overweight and obese: a systematic review and meta-analysis

Phaseolus vulgaris extract affects glycometabolic and appetite control in healthy human subjects.

A Dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women.

Proprietary alpha-amylase inhibitor formulation from white kidney bean (Phaseolus vulgaris L.) promotes weight and fat loss: a 12-week, double-blind, placebo-controlled, randomized trial

The efficacy of Phaseolus vulgaris as a weight-loss supplement: a systematic review and meta-analysis of randomised clinical trials.

Weight reduction and maintenance with IQP-PV-101: a 12-week randomized controlled study with a 24-week open label period.