Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we’ll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more about cookies
Head-to-head evidence comparison — which supplement is right for you?
Feverfew vs Iron: Iron has the stronger overall evidence (9 vs 5/10); the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Iron wins 3 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Likely helps
10 of 14 studies with measurable effects showed benefit.
Top outcomes
100-300mg feverfew leaf/extract daily, standardized to ≥0.2-0.7% parthenolide (stable CO2 extract preferred)
with-meals
Standardized CO2 extract (parthenolide-standardized)
18-45mg elemental iron for deficiency (varies by severity)
On empty stomach if tolerated, Away from tea, coffee, dairy
Ferrous bisglycinate (gentle, well-absorbed) or iron protein succinylate
and 6 more not shown
4-12 weeks
4-8 weeks
Days
On discontinuation
2-4 weeks
4-8 weeks
4-12 weeks
A Critical Approach to Evaluating Clinical Efficacy, Adverse Events and Drug Interactions of Herbal Remedies.
Phytotherapy research : PTR (2016) · Meta analysis
Critical appraisal of systematic-review/meta-analysis evidence
Feverfew for migraine prophylaxis: a systematic review.
Journal of dietary supplements (2009) · Systematic review
Some trials showed fewer migraine attacks
Feverfew for preventing migraine.
The Cochrane database of systematic reviews (2015) · Systematic review
Six trials (561 patients) met inclusion criteria, one new since the 2004 edition
Daily oral iron supplementation during pregnancy
The Cochrane database of systematic reviews (2024) · Meta analysis · n=48971
There is probably little to no difference in maternal death (2 versus 4 events, RR 0.57, 95% CI 0.12 to 2.69; 3 trials, 14,060 women; moderate-certainty evidence).
The Prevalence of Anemia among Pregnant Women in China: A Systematic Review and Meta-Analysis
Nutrients (2024) · Meta analysis · n=722
The results showed that the prevalence of anemia, ID, and IDA among pregnant women in China were 30.7% (95% CI: 26.6%, 34.7%), 45.6% (95% CI: 37.0%, 54.2%), and 17.3% (95% CI: 13.9%, 20.7%), respectively.
Treatment for women with postpartum iron deficiency anaemia
The Cochrane database of systematic reviews (2024) · Meta analysis · n=572
Intravenous iron versus oral iron supplementation The evidence is very uncertain about the effect of intravenous iron on mortality (risk ratio (RR) 2.95, 95% confidence interval (CI) 0.12 to 71.96; P = 0.51; I² = not applicable; 3 RCTs; 1 event; 572 women; very low-certainty evidence).
Based on meta-analyses showing hemoglobin improvements of 2.01-5.30 g/dL in iron deficient populations. Higher doses show diminishing returns with increased GI side effects. Effectiveness varies significantly by baseline iron status and form used.
AI-estimated from published studies. Interpret as directional guidance.
Iron has a higher evidence score (9/10 vs 5/10) and wins in 3 of 3 categories.
No known interactions between Feverfew and Iron have been documented in our database. However, always consult a healthcare provider before combining supplements.
Magnesium, riboflavin, CoQ10 — the supplements with real migraine-prevention evidence (and doses).
On Ozempic/Wegovy/Mounjaro? What actually helps — muscle preservation, GI relief, nutrient gaps (no upsell).
Tired? Why most "energy" pills only work if they fix a deficit — and how to find yours first.
Selenium helps; iodine can WORSEN Hashimoto’s. The honest take on "thyroid support".
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.