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Head-to-head evidence comparison — which supplement is right for you?
Sulforaphane wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
8 of 10 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
6 of 7 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Green Tea Extract and Sulforaphane have evidence — compare verdict strength side-by-side.
250-500mg EGCG (or 500-1000mg green tea extract)
With meals, Morning or pre-exercise
Standardized extract (45-50% EGCG)
10-50mg sulforaphane (or equivalent from broccoli sprout extract)
With meals, Morning preferred
Stabilized sulforaphane (Prostaphane, Avmacol) or broccoli sprout extract with myrosinase
Acute and 4-8 weeks
Acute
30-60 minutes
2-4 weeks
2-4 weeks
1-2 weeks
Green tea (Camellia sinensis) for the prevention of cancer
The Cochrane database of systematic reviews (2020) · Meta analysis · n=1795
For incident prostate cancer, the summary risk ratio (RR) in the green tea-supplemented participants was 0.50 (95% confidence interval (CI) 0.18 to 1.36), based on three studies and involving 201 participants (low-certainty evidence).
Impact of flavan-3-ols on blood pressure and endothelial function in diverse populations: a systematic review and meta-analysis of randomized controlled trials
European journal of preventive cardiology (2025) · Meta analysis · n=5205
Flavan-3-ol interventions included epicatechin, epigallocatechin-gallate, cocoa products, tea, grape extract, and apples delivering 586 mg (95% CI 510, 662) total flavan-3-ols.
The effects of green tea extract supplementation on body composition, obesity-related hormones and oxidative stress markers: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials
The British journal of nutrition (2024) · Meta analysis · n=3802
Pooled effect sizes indicated that BM, BFP, BMI and MDA significantly reduced following GTE supplementation.
Broccoli Consumption and Risk of Cancer: An Updated Systematic Review and Meta-Analysis of Observational Studies
Nutrients (2024) · Meta analysis · n=31292
In summary, the findings indicate that individuals suffering from some type of cancer consumed less broccoli, suggesting a protective biological effect of broccoli on cancer.
Do Brassica Vegetables Affect Thyroid Function?-A Comprehensive Systematic Review
International journal of molecular sciences (2024) · Systematic review
We analyzed the results of 123 articles of in vitro, animal, and human studies, describing the impact of brassica plants and extracts on thyroid mass and histology, blood levels of TSH, T3, T4, iodine uptake, and the effect on thyroid cancer cells.
Potential Effects of Bioactive Compounds of Plant-Based Foods and Medicinal Plants in Chronic Kidney Disease and Dialysis: A Systematic Review
Nutrients (2024) · Systematic review
Systematic review examining Sulforaphane efficacy
Based on meta-analysis showing 9.29 mg/dl LDL reduction with 107-856 mg/d EGCG. Optimal cardiovascular benefits observed at 400-500 mg/day. Take with food to reduce GI side effects.
Based on meta-analyses showing significant improvements in Social Responsiveness Scale and irritability/hyperactivity scores. Effects were modest and required 4-10 weeks of supplementation. Limited to autism populations only.
AI-estimated from published studies. Interpret as directional guidance.
Sulforaphane has a higher evidence score (5.5/10 vs 7.5/10) and wins in 2 of 3 categories.
For healthy aging, Sulforaphane has a higher relevance score (85 vs 70).
No known interactions between Green Tea Extract and Sulforaphane have been documented in our database. However, always consult a healthcare provider before combining supplements.