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Head-to-head evidence comparison — which supplement is right for you?
Probiotics wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Probably helps
4 of 6 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
30 of 39 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Hawthorn and Probiotics have evidence — compare verdict strength side-by-side.
160-900mg extract (standardized to 2-3% flavonoids or 18-20% OPCs)
With meals, Split into 2-3 doses
Standardized extract (WS 1442 or LI 132 are most studied)
10-20 billion CFU
With or without food (strain-dependent), Same time daily for consistency
Capsules with multiple strains
8-12 weeks
6-12 weeks
2-4 weeks
4-8 weeks
4-8 weeks
First 1-2 weeks
Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis
Stroke and vascular neurology (2022) · Meta analysis · n=6339
Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone.
Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials
The American Journal of Medicine (2003) · Meta analysis · n=632
Eight trials including 632 patients with chronic heart failure (NYHA classes I to III) provided data suitable for meta-analysis.
Traditional Chinese medicines benefit to nonalcoholic fatty liver disease: a systematic review and meta-analysis
Molecular biology reports (2012) · Meta analysis · n=25661
Comparing with western medicines mentioned above, TCM had a better effect on the normalization of alanine aminotransferase and disappearance of radiological steatosis in the treatment of NAFLD.
Preventive Effect of Probiotics on Oral Mucositis Induced by Cancer Treatment: A Systematic Review and Meta-Analysis
International journal of molecular sciences (2022) · Meta analysis · n=708
Three trials using Lactobacilli-based probiotics reported that the incidence of oral mucositis in the probiotic group was significantly low (risk ratio [RR] = 0.84, 95% confidence interval [CI] = 0.77−0.93, p = 0.0004).
Probiotics for treating acute infectious diarrhoea
The Cochrane database of systematic reviews (2020) · Meta analysis · n=12127
Effect size was similar in the sensitivity analysis and marked heterogeneity persisted.
Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
The Cochrane database of systematic reviews (2017) · Meta analysis · n=9955
A complete case analysis (i.e. participants who completed the study) among trials investigating CDAD (31 trials, 8672 participants) suggests that probiotics reduce the risk of CDAD by 60%.
Based on meta-analysis showing 7-watt improvement in maximal workload. Effects primarily documented in mild heart failure patients. Most studies used WS 1442 extract standardized to 18.75% oligomeric procyanidins.
Based on meta-analyses showing benefits for IBS and digestive symptoms. Effect sizes varied considerably between studies with low to very low certainty of evidence. Initial GI symptoms common when starting but typically resolve within 1-2 weeks.
AI-estimated from published studies. Interpret as directional guidance.
Probiotics has a higher evidence score (9/10 vs 6.5/10) and wins in 2 of 3 categories.
For reduce inflammation, Probiotics has a higher relevance score (95 vs 90).
No known interactions between Hawthorn and Probiotics have been documented in our database. However, always consult a healthcare provider before combining supplements.