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Head-to-head evidence comparison — which supplement is right for you?
Lavender vs Skullcap: Lavender has the stronger overall evidence (7.2 vs 4/10); they're alternatives for reduce anxiety & stress — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Lavender wins 3 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Too few graded studies
Top outcomes
Verdict
Mostly mechanism / observational
Top outcomes
80 mg oral Silexan daily OR aromatherapy inhalation 30–60 min sessions
Evening before bed for sleep and anxiety, Acute use before stressful procedures or events
Oral Silexan capsule (80 mg) for systemic/psychiatric use
350-450mg dried herb OR 1-2ml tincture (1:5), up to 3x daily
Before bed for sleep, During day for anxiety as needed
Fresh plant tincture (most traditional)
1–4 weeks
1–3 weeks
4–8 weeks
Acute to 2 weeks
30-60 minutes
30-60 minutes before bed
Effects of lavender on anxiety: A systematic review and meta-analysis.
Phytomedicine : international journal of phytotherapy and phytopharmacology (2019) · Meta analysis · n=3964
65 RCTs and 25 non-randomised studies were reviewed, and 37 RCTs (3,964 participants) were pooled.
Efficacy of Silexan in patients with anxiety disorders: a meta-analysis of randomized, placebo-controlled trials.
European archives of psychiatry and clinical neuroscience (2023) · Meta analysis · n=1213
Five double-blind placebo-controlled trials of Silexan 80 mg/day for ten weeks in adult outpatients with subthreshold anxiety, mixed anxiety and depressive disorder or generalised anxiety disorder were pooled (n = 1,213).
Efficacy of Silexan in subthreshold anxiety: meta-analysis of randomised, placebo-controlled trials.
European archives of psychiatry and clinical neuroscience (2019) · Meta analysis · n=697
Pooled individual patient data from three placebo-controlled trials in subthreshold anxiety (697 patients), Silexan 80 mg/day for 10 weeks.
Baicalin and baicalein against myocardial ischemia-reperfusion injury: A review of the current documents
Tissue & cell (2025) · Review
Research in both animal and cell models suggests that these flavonoids, especially baicalin, can restore cardiac health following MIRI, improving cardiac performance, and reducing cardiac damage.
Promising Role of the Scutellaria baicalensis Root Hydroxyflavone-Baicalein in the Prevention and Treatment of Human Diseases
International journal of molecular sciences (2023) · Review
It has been documented that the extract of Baikal skullcap (Scutellaria baicalensis) has hepatoprotective, calming, antiallergic, and anti-inflammatory properties.
Wogonin and its analogs for the prevention and treatment of cancer: A systematic review
Phytotherapy research : PTR (2022) · Systematic review
WOG, in combination with established chemotherapeutic drugs, improves the efficacy of treatment and lowers toxicity.
Lavender has a higher evidence score (7.2/10 vs 4/10) and wins in 3 of 3 categories.
For reduce anxiety & stress, Lavender has a higher relevance score (90 vs 75).
No documented interaction was found in the data searched. This does not establish that this exact combination is safe.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.