Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we'll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more
Head-to-head evidence comparison — which supplement is right for you?
Ornithine and Tart Cherry are closely matched across evidence, studies, and safety.
Verdict
Likely helps
3 of 4 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
12 of 12 studies with measurable effects showed benefit.
Top outcomes
2-6g daily
Before exercise for fatigue reduction, Before bed for sleep support
L-Ornithine HCl
480-500mg extract or 240ml (8oz) juice twice daily
Morning and evening, Before/after exercise for recovery
Concentrated Montmorency tart cherry extract (capsules)
During prolonged exercise
Hours post-exercise
1-2 weeks
Immediate
1-2 weeks
Same day/next day
1-3 days
N/A
Comparative Efficacy of Treatment Options for Minimal Hepatic Encephalopathy: A Systematic Review and Network Meta-Analysis
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association (2020) · Meta analysis · n=1563
In a meta-analysis of data from 25 trials, we found rifaximin and lactulose to be most effective for reversal of minimal HE in patients with cirrhosis.
Safety assessment of L-ornithine oral intake in healthy subjects: a systematic review
Amino acids (2025) · Systematic review
The main observed adverse events were gastrointestinal disorders.
Efficacy of L-ornithine L-aspartate for minimal hepatic encephalopathy in patients with cirrhosis: A meta-analysis of randomized controlled trials
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology (2024) · Meta analysis · n=292
LOLA has significant beneficial effects on reversal of MHE and prevention of OHE in patients with cirrhosis compared with placebo or no intervention.
Effects of dietary supplements on athletic performance in elite soccer players: a systematic review
Journal of the International Society of Sports Nutrition (2023) · Systematic review · n=1043
Nitrate-rich beetroot concentrate can attenuate performance decrease in the days following matches.
Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials
Journal of the International Society of Sports Nutrition (2021) · Meta analysis
No effect on exercise performance following consumption of foods rich in L-citrulline was identified (SMD=-0.03, p=0.24).
Efficacy, acceptability, and tolerability of all available treatments for insomnia in the elderly: a systematic review and network meta-analysis
Acta psychiatrica Scandinavica (2020) · Meta analysis · n=6832
Insufficient evidence exists on which intervention is more efficacious for elderly patients with insomnia.
Evidence specific to L-ornithine L-aspartate form in cirrhosis patients. Meta-analysis of 292 patients showed significant benefit vs placebo. GI adverse events noted as main side effect. Limited applicability to healthy populations.
Meta-analysis showed small beneficial effect (ES = -0.44). Multiple studies but limited sample sizes. Effect appears modest and variable between individuals.
AI-estimated from published studies. Interpret as directional guidance.
Both Ornithine and Tart Cherry are closely matched — the best choice depends on your specific health goals.
For speed up recovery, Tart Cherry has a higher relevance score (85 vs 60).
No known interactions between Ornithine and Tart Cherry have been documented in our database. However, always consult a healthcare provider before combining supplements.