Compare Supplements

Side-by-side comparison of 2 supplements

Caf9.5

Caffeine

Moderate safety

NR7.2

Nicotinamide Riboside

High safety

Evidence

Evidence Score9.5/10

Studies: 146

Meta-analyses: 23

Evidence Score7.2/10

Studies: 32

Meta-analyses: 5

Outcome Grades

Boost daily energyA

Sharpen focusA

Improve memory & learningC

Speed up recoveryC

Boost daily energyB

Sharpen focusC

Improve memory & learningC

Speed up recoveryC

A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.

Dosage & timing

Dosage:

200mg

Best Time:

Morning · with food (preferred)

Can take on empty stomach

Form:

Pill/capsule for precise dosing

Dosage:

500mg

Best Time:

Morning · with food (preferred)

Take with food

Form:

Nicotinamide Riboside Chloride capsules or powder

What you'll notice

👁️ Increased Alertness95%

15-45 minutes

🎯 Improved Focus85%

30-60 minutes

🏃 Better Exercise Performance80%

30-60 minutes

📈 Elevated Blood NAD+ Levels95%

1–2 weeks

⚡ Improved Energy & Reduced Fatigue55%

4–8 weeks

🧠 Cognitive Stability45%

8–16 weeks

Safety

Moderate safety

Contraindications:

Severe anxiety disorders
Uncontrolled high blood pressure
Heart arrhythmias

Drug Interactions:

Stimulant medications (Adderall, etc.)
MAO inhibitors
Certain antibiotics (Cipro)

Side Effects:

Jitteriness/anxietyInsomniaIncreased heart rate

High safety

Contraindications:

Known hypersensitivity to nicotinamide riboside or niacin derivatives
Active cancer or cancer history: NAD+ elevation may theoretically support tumor cell metabolism (consult oncologist before use)
Severe hepatic impairment: high-dose NAD+ precursors may affect liver metabolism

Drug Interactions: