We use essential cookies (authentication, your saved goals/stack) by default. With your permission we'll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more
A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.
Direct side-by-side from the meta-analysis. Each row is an outcome where ≥2 of your selected supplements have pooled data. Best effect per row highlighted.
| Outcome | DHEA | Methylfolate |
|---|---|---|
| Support mood — Depression − better · points (PHQ-9) | −1.3best moderate | −2.6 weak |
75mg
Morning · with food
Micronized DHEA capsules
7500mcg
Morning · with food (preferred)
L-Methylfolate (5-MTHF)
4-8 weeks
8-12 weeks
2-4 weeks
1-3 weeks
4-8 weeks
Like what you see? Add these to your stack.
See how they work together through biological pathways.
Build Your StackWant to compare more supplements?