Wir verwenden standardmäßig essenzielle Cookies (Anmeldung, deine gespeicherten Ziele/Stacks). Mit deiner Erlaubnis aktivieren wir außerdem datenschutzfreundliche Analytik (Vercel Web Analytics, anonyme Ladezeit-Metriken) und Fehler-Replay-Diagnostik (Sentry — DOM-Snapshots nur, wenn ein Fehler auftritt), damit wir Bugs schneller beheben können. Mehr über Cookies erfahren

Pj1.0

Poleiminze (Pennyroyal) – Forschung

Zu wenige bewertete Studien

6 begutachtete Studien

Was die Evidenz sagt

Überwiegend Mechanismus / Beobachtung

Die meisten Studien zu Poleiminze (Pennyroyal) sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.

Die meiste Evidenz stammt aus hochwertigen Studien, veröffentlicht 1996–2025 mit einer typischen Studiengröße von 142 Teilnehmenden.

Basierend auf 6 Studien · 142 Teilnehmende insgesamt

Konfidenz

Geringe Konfidenz

Nach Outcome

Safety profile
Zu wenige bewertete Studien1 Studie

Aktives Forschungsgebiet

4 Studien in den letzten 5 Jahren

199620102025

1Fallstudie1996

Einfach gesagt: Pennyroyal is a widely available herb that has long been used as an abortifacient despite its potentially lethal hepatotoxic effects.

Anderson IB et al. · Ann Intern Med (1996)

First quantification of pennyroyal metabolites in human overdose
Protein-bound adducts of the metabolites detected in human liver
Places the two cases in the context of previously reported pennyroyal poisoning

Quelle ansehen

2Übersicht2025

Einfach gesagt: This study aimed to provide an overview on the two species' composition and biological activities to review the applications of their crude extracts and EOs in agriculture as natural pesticides to protect different cultures and in food industry to produce biobased food packaging.

Khodja NK, Brahmi F, Zebiri F, Ouchene A, Bradai YD, Madani K. · Chemistry & biodiversity (2025)

Considering plant extracts and phytochemicals have biological action both in vitro and in vivo, plants are being used as alternative sources in agriculture and food industry.
Mentha pulegium L. and Salvia officinalis L. from the Lamiaceae family are some of the most popular and widely utilized medicinal plants due to their bioactive compounds such as essential oils (EOs) and phenolics, which have powerful antioxidant and antimicrobial characteristics.
It is evident that these plants have also a variety of applications due to their various components and concentrations.

Quelle ansehen

3Übersicht2025

Einfach gesagt: Additionally, recent advances in producing herbal medicine formulations based on nanoparticle technologies are also summarised in this review article.

Rana A, Mittal A, Vashist C, Rajput S, Sridhar SB, Sharma S, Malviya R. · Current topics in medicinal chemistry (2025)

To efficiently administer herbal medications, nanoparticulate formulations such as microemulsions, solid lipid nanoparticles, polymeric nanoparticles, liposomes, and proliposomes are being considered.
This article aims to effectively examine the ability of herbal drugs that contain NP to combat microorganisms as well as a variety of herbal plants with antibacterial properties, including thyme, clove, garlic, mallow, chamomile, and mentha pulegium.
This comprehensive analysis is timely and necessary since nanotechnology is a promising prospect in infectious disease treatment.

Quelle ansehen

4Übersicht2025

Einfach gesagt: These plants are potent antifeedants, and at the same time provide sufficient biomass for industrial use in the development and production of botanical antifeedants.

Pavela R, Kovaříková K, Novák M. · Insects (2025)

Another promising approach is the use of plant antifeedants, which can significantly reduce the food intake of phytophagous insects.
The selection was based on a comparison of effective concentrations or doses.
Effective extracts were obtained from 85 plant species belonging to 35 families and the EOs came from 38 aromatic plant species from 11 families.

Quelle ansehen

5Übersichtn=142 · medium study2024

Einfach gesagt: Conclusion These results reflect the interesting traditional medical knowledge of this population, which merits being documented.

El-Yagoubi K, Bakour M, Lyoussi B. · Avicenna journal of phytomedicine (2024)

However, 34 interviewers prefer conventional medicine.
Date palm fruits and oregano were the most commonly used medicinal plants by the Daraa Tafilalet population to enhance the immune system, followed by anise, lavender, rosemary, thyme, and pennyroyal.
These results are supported by literature data.

Quelle ansehen

6Übersicht2015

Einfach gesagt: One example is the hepatotoxicity of pennyroyal oil, which is ingested as an abortifacient, among other uses.

Gordon P et al. · Drug Metab Rev (2015)

Three decades of mechanistic work on how pulegone injures the liver
Places pennyroyal alongside kava, chaparral and germander as herbal causes of liver injury
Notes that adverse effects of herbal supplements are widely under-reported

Quelle ansehen

In der Forschungsbibliothek ansehen

Poleiminze (Pennyroyal) – Forschung

Überwiegend Mechanismus / Beobachtung

Pennyroyal toxicity: measurement of toxic metabolite levels in two cases and review of the literature.

Mentha pulegium L. and Salvia officinalis L. Bioactive Compounds: Focus on Their Application in Agriculture and Food Packaging

Advancements in Herbal Drug Loaded Nanoparticulate System for Antimicrobial Effect

Botanical Antifeedants: An Alternative Approach to Pest Control

Medicinal plants used in traditional medicine to enhance immunity: A survey in the southeastern area of Morocco and a literature review

A decades-long investigation of acute metabolism-based hepatotoxicity by herbal constituents: a case study of pennyroyal oil.