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Rsv4.5
Resveratrol – Forschung
Hilft wahrscheinlich
194 begutachtete Studien
Was die Evidenz sagt
Hilft wahrscheinlich
Resveratrol scheint in 10 von 11 Studien mit messbaren Effekten zu helfen — die Evidenz tendiert klar ins Positive.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2011–2026 mit einer typischen Studiengröße von 166 Teilnehmenden.
Basierend auf 194 Studien · 61 Meta-Analysen · 75 RCTs · 21,732 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
10geholfen1unklar· 183 weitere ohne bewertete Effektdaten
Nach Outcome
Heart & blood pressureVerbessert die Endothelfunktion in gepoolten Studien geringfügig · 4-8 Wochen
Hilft wahrscheinlich185 Studien
Glucose & metabolicReduziert die Insulinresistenz bei Typ-2-Diabetes; kein Anti-Adipositas-Effekt · 8-12 Wochen
Hilft wahrscheinlich32 Studien
InflammationSenkt CRP und TNF-a in einigen Studien geringfügig · 4-8 Wochen
Skin healthAntioxidatives/Sirtuin-basiertes Anti-Aging; orale Evidenz für die Haut schwach (topisch stärker) · 12 Wochen
Zu wenige bewertete Studien1 Studie
Vision & eye health
Zu wenige bewertete Studien1 Studie
In Zahlen
Aus 47 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
77%
über Studien hinweg
Untersuchte Personen
22k
typische Studie: 166 Personen
Stärkste Designs
136
61 gepoolt, 75 randomisiert
Zeigte Nutzen
91%
10/11 Studien
Wie lange Studien liefen
1–3 Monate
1
3+ Monate
3
Untersuchte Populationen
Adults4
General population3
Patients with Type 2 Diabetes2
Women with PCOS2
Aktives Forschungsgebiet
125 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2026
201120182026
1DAS28 improvementMeta-Analysen=3,852 · very large study2023
Einfach gesagt: Dietary polyphenols may improve DAS28, reduce C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), and improve oxidative stress, etc.
Long Z et al. · Frontiers in immunology (2023)
Dietary polyphenols may improve DAS28, reduce C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), and improve oxidative stress, etc.
However, more RCTs are needed to verify or modify the efficacy and safety of dietary polyphenols.
3BMI reductionMeta-Analysen=2,173 · very large study2022
Einfach gesagt: Based on current evidence, curcumin can reduce BMI, TG, TC, liver enzymes, and insulin resistance; catechin can reduce BMI, insulin resistance, and TG effectively; silymarin can reduce liver enzymes.
Yang K et al. · Frontiers in immunology (2022)
Based on current evidence, curcumin can reduce BMI, TG, TC, liver enzymes, and insulin resistance; catechin can reduce BMI, insulin resistance, and TG effectively; silymarin can reduce liver enzymes.
For resveratrol, naringenin, anthocyanin, hesperidin, and catechin, more RCTs are needed to further evaluate their efficacy and safety.
4Inflammatory markers (TNF-α, hs-CRP)Meta-Analysen=736 · large study2018
Einfach gesagt: Available evidence from RCTs suggests that resveratrol supplementation significantly reduced TNF-α and hs-CRP levels.
Koushki M et al. · Clinical Therapeutics (2018)
The results of meta-analysis found significant reductions in the level of TNF-α (WMD, -0.44; 95% CI, -0.71 to -0.164; P = 0.002) and hs-CRP (WMD, -0.27; 95% CI, -0.5 to -0.02; P = 0.033) after supplementation with resveratrol.
Resveratrol supplementation had no significant effect on the level of IL-6 (WMD, -0.16; 95% CI, -0.53 to 0.20; P = 0.38).
Seventeen RCTs, including 736 subjects, fulfilled the eligibility criteria.
5Multiple health outcomes across 24 indicationsSystematische Übersichtn=200 · medium study2024
Einfach gesagt: In conclusion, over the last 20 years, the increasing weight of clinical evidence suggests resveratrol can benefit human health, but more large, high-quality clinical trials are required to transition this intriguing compound from health food shops to the clinic.
Brown K et al. · International journal of molecular sciences (2024)
Over the last 20 years, there have been almost 200 studies evaluating resveratrol across at least 24 indications, including cancer, menopause symptoms, diabetes, metabolic syndrome, and cardiovascular disease.
There are currently no consensus treatment regimens for any given condition or endpoint, beyond the fact that resveratrol is generally well-tolerated at a dose of up to 1 g/day.
Additionally, resveratrol consistently reduces inflammatory markers and improves aspects of a dysregulated metabolism.
6Skin wound healing improvementSystematische Übersichtn=826 · large study2022
Einfach gesagt: The included studies showed promising results that resveratrol might be a feasible treatment approach to support wound healing, counteract excessive scarring, and even prevent photo-aging of the skin.
Hecker A et al. · International wound journal (2022)
The literature search yielded a total of 826 studies, but only 41 studies met the inclusion criteria.
The included studies showed promising results that resveratrol might be a feasible treatment approach to support wound healing, counteract excessive scarring, and even prevent photo-aging of the skin.
Resveratrol represents an interesting and promising novel therapy regime but to confirm resveratrol-associated effects, more evidence based in vitro and in vivo studies are needed.
9Testosterone reductionMeta-Analysen=218 · medium study2023
Einfach gesagt: In combination with other treatments, especially for hyperlipidemia, resveratrol is beneficial for women diagnosed with PCOS.Copyright: Hammad Ali Fadlalmola et al.
Ali Fadlalmola H et al. · The Pan African medical journal (2023)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
With 95% confidence intervals, the data was retrieved and analyzed as a mean difference (MD) or a standardized mean difference (SMD).
Resveratrol significantly reduced testosterone (SMD = -0.40; 95% CI [-0.71, -0.10], P = 0.009), luteinizing hormone (LH) (SMD = -0.32; 95% CI [-0.62, 0.01], P = 0.04), and dehydroepiandrosterone sulfate (DHEAS) (MD = -0.85; 95% CI [-1.25, -0.45], P < 0.0001) compared with the placebo.
Four RCTs with 218 women were included in the analysis.
10Prolactin levels improvementMeta-Analysen=84 · small study2024
Einfach gesagt: As per the results of our analysis, resveratrol demonstrates mild therapeutic potential for the sufferers of PCOS, and cannot replace the current established treatment guidelines.
Larik MO et al. · Endocrine (2024)
Likely real
It was observed that resveratrol significantly improved prolactin levels (P = 0.02), acne scores (P = 0.008), and total cholesterol (P = 0.02).
However, there were no significant improvements observed with respect to total testosterone, follicle stimulating hormone (FSH), lutenizing hormone (LH), body mass index (BMI), hirsutism scores, triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein (LDL).
As per the results of our analysis, resveratrol demonstrates mild therapeutic potential for the sufferers of PCOS, and cannot replace the current established treatment guidelines.