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Shv5.0
Shatavari – Forschung
Hilft wahrscheinlich
19 begutachtete Studien
Was die Evidenz sagt
Hilft wahrscheinlich
Shatavari scheint in 5 von 5 Studien mit messbaren Effekten zu helfen — die Evidenz tendiert klar ins Positive.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2012–2026 mit einer typischen Studiengröße von 45 Teilnehmenden.
Basierend auf 19 Studien · 1 Meta-Analyse · 6 RCTs · 2,506 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
5geholfen· 14 weitere ohne bewertete Effektdaten
Nach Outcome
Women's healthEine kleine RCT (n=50) reduzierte perimenopausale vasomotorische Symptome · 4-8 weeks · Eine kleine perimenopausale RCT verbesserte hormonelle Marker · 4-8 weeks · Eine kleine RCT verbesserte die Scores für menstruelle Beschwerden · 1-3 cycles
Hilft wahrscheinlich19 Studien
Muscle strength & power
Überwiegend Mechanismus / Beobachtung3 Studien
Anxiety & stressAdaptogene Aussagen beruhen auf begrenzter, überwiegend traditioneller Evidenz · 4-8 weeks · Die adaptogene Unterstützung beruht auf begrenzter, überwiegend traditioneller Evidenz · 4-8 weeks
Überwiegend Mechanismus / Beobachtung3 Studien
Therapeutic & clinical
Überwiegend Mechanismus / Beobachtung3 Studien
Safety profile
Überwiegend Mechanismus / Beobachtung3 Studien
Fertility & reproductiveDer Fruchtbarkeitsnutzen ist in Humanstudien weitgehend unbelegt · 4-12 weeks
Zu wenige bewertete Studien2 Studien
Bone health
Zu wenige bewertete Studien2 Studien
In Zahlen
Aus 13 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
100%
über Studien hinweg
Untersuchte Personen
2,506
typische Studie: 45 Personen
Stärkste Designs
7
1 gepoolt, 6 randomisiert
Zeigte Nutzen
100%
5/5 Studien
Wie lange Studien liefen
1–3 Monate
1
3+ Monate
1
Untersuchte Populationen
Breastfeeding mothers2
Not specified1
Women of reproductive age1
Women1
Aktives Forschungsgebiet
15 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2020
201220192026
1Pharmacological pathways modulated by Asparagus saponinsSystematische Übersicht2026
The uses of this plant in some of the marketed traditional products, nano-formulations and clinical trial aspects have also been included.
Kurmi A et al. · Chemistry & biodiversity (2026)
Shatavarin-IV is regarded as the most important steroidal saponin responsible for most of the pharmacological effects of Shatavari.
The present review provides an update on the diverse pharmacological activities of 'Shatavari' and Shatavarin-IV.
It covers plant metabolic biosynthesis, recent mechanistic pathways underlying key bioactivities and safety aspects.
2Shatavari efficacy for fertilitySystematische Übersicht2025
Shatavari shows promise for fertility enhancement due to its active compounds like saponins and flavonoids.
Oyovwi MO et al. · Current nutrition reports (2025)
Recent investigations suggest that Shatavari has the potential to enhance fertility rates and improve breast milk quality and quantity, making it important for postpartum care.
Preliminary findings also indicate positive outcomes for male fertility, but more clinical trials are needed.
It is also crucial for pregnant and breastfeeding women to consult healthcare professionals before using Shatavari due to potential interactions and contraindications.
3Health benefits of Asparagus racemosusSystematische ÜbersichtCited 1×2025
Shatavarin IV, a sarsapogenin enriched in the roots of Shatavari, is especially beneficial for women's reproductive health and also acts as an effective stressbuster.
Banerjee P et al. · Journal of the American Nutrition Association (2025)
In this regard, a novel Asparagus root formulation, Shevari4T®, has been developed, with Shatavarin IV content exceeding 7.4%, which promises to deliver the goodness of Shatavari, especially for women.
Shatavarin IV, a sarsapogenin enriched in the roots of Shatavari, is especially beneficial for women's reproductive health and also acts as an effective stressbuster.
These compounds are frequently used in the treatment of several medical conditions, including dysentery, diabetic retinopathy, hypertension, anxiety disorders, inflammation, tumors, mental disorders, hyperacidity, viral diseases, spasms, chronic fever, and rheumatism.
4Breast milk volumeMeta-AnalyseCited 62×n=20 · very small study2020
Due to extremely limited, very low certainty evidence, we do not know whether galactagogues have any effect on proportion of mothers who continued breastfeeding at 3, 4 and 6 months.
Foong SC et al. · The Cochrane database of systematic reviews (2020)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Only one study (metoclopramide) reported on the outcome of infant weight, finding little or no difference (mean difference (MD) 23.0 grams, 95% confidence interval (CI) -47.71 to 93.71; 1 study, 20 participants; low-certainty evidence).
Three studies (metoclopramide, domperidone, sulpiride) reported on milk volume, finding pharmacological galactagogues may increase milk volume (MD 63.82 mL, 95% CI 25.91 to 101.72; I² = 34%; 3 studies, 151 participants; low-certainty evidence).
Three studies (fennel, fenugreek, moringa, mixed botanical tea) reported infant weight but could not be meta-analysed due to substantial clinical and statistical heterogeneity (I2 = 60%, 275 participants, very low-certainty evidence).
Well-designed and well-conducted clinical trials that address the above limitations are necessary to generate a body of evidence as a basis for recommendations regarding herbal galactogogues.
Mortel M et al. · Journal of human lactation : official journal of International Lactation Consultant Association (2013)
Five trials found an increase in breast milk production.
Several limitations exist that affect the validity of the trial results, including small sample size, insufficient randomization methods, poorly defined eligibility criteria, use of poly-herbal interventions, and variable breastfeeding practices among enrolled subjects.
Given the insufficiency of evidence from these trials, no recommendation is made for the use of herbs as galactogogues.
6Effects of shatavari on female reproductive health disordersSystematische ÜbersichtCited 55×2018
Although shatavari is one of the major health tonics and most popular rasayana drugs to treat reproductive ailments of women, underlying mechanism of shatavari action at the level of ovary remains ...
Pandey AK et al. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2018)
Although shatavari is one of the major health tonics and most popular rasayana drugs to treat reproductive ailments of women, underlying mechanism of shatavari action at the level of ovary remains poorly understood.
Further studies are required to elucidate the mechanism of shatavari actions at the level of ovary and oocyte that directly impacts the reproductive health of women.
7Use of galactogogues in breastfeeding mothersSystematische ÜbersichtCited 56×2012
Nonpharmacologic recommendations should be exhausted before adding therapy.
Forinash AB et al. · The Annals of pharmacotherapy (2012)
Nonpharmacologic recommendations should be exhausted before adding therapy.
Although anecdotal evidence encourages the use of metoclopramide, fenugreek, asparagus, and milk thistle for their galactogogue properties, efficacy and safety data in the literature are lacking.
Oxytocin and domperidone are potentially available for compounding purposes, but safety data are limited.
9Vasomotor symptoms and menstrual healthRCTn=50 · small study2025
CL22205 effectively reduces VMS, menstrual discomfort, and hormonal imbalances while improving skin and hair health, offering a safe and natural alternative for perimenopausal symptoms management.
Yadav P et al. · Journal of the American Nutrition Association (2025)
Sehr groß Nutzen
← SchlechterKein EffektBesser →
Likely real
CL22205 significantly reduced (p < 0.001) total MRS scores and HFWWS vs. placebo and baseline after 120 days of treatment, menstrual symptoms (congestive and spasmodic dysmenorrhea) were improved (p < 0.001).
CL22205 decreased serum FSH (56.3%), LH (34.3%), and increased AMH (188.1%, p < 0.001) levels.
CL22205 effectively reduces VMS, menstrual discomfort, and hormonal imbalances while improving skin and hair health, offering a safe and natural alternative for perimenopausal symptoms management.
12Handgrip strength and myosin regulatory light chain phosphorylationRCTCited 13×n=10 · very small study2021
Shatavari may improve muscle function and contractility via myosin conformational change and further investigation of its utility in conserving and enhancing musculoskeletal function, in larger and more diverse cohorts, is warranted.
O'Leary MF et al. · Nutrients (2021)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
Handgrip (but not knee extensor) strength was improved by shatavari supplementation (shatavari +0.7 ± 1.1 kg, placebo -0.4 ± 1.3 kg; p = 0.04).
Myosin regulatory light chain phosphorylation, a known marker of improved myosin contractile function, was increased in VL following shatavari supplementation (immunoblotting; placebo -0.08 ± 0.5 a.u., shatavari +0.3 ± 1 arbitrary units (a.u.); p = 0.03).
Shatavari increased the phosphorylation of Aktser473 (Aktser473 (placebo -0.6 ± 0.6 a.u., shatavari +0.2 ± 1.3 a.u.; p = 0.03) in VL.
13Systematische Übersichtn=1,541 · large study2026
PROSPERO Registration Number CRD42023412915 (12th April 2023).
Walter F, Schalla J, Bloch W, Diel P, Geisler S, Isenmann E. · Sports medicine - open (2026)
However, the evidence supporting the effectiveness of additional nutritional and supplementation strategies remains inconclusive.
While a calorie-restricted diet and adequate protein intake appear to promote favourable changes in body composition, the available data is still insufficient to derive specific and evidence-based recommendations regarding supplementation in conjunction with strength training.
PROSPERO Registration Number CRD42023412915 (12th April 2023).
Integrating these botanicals into modern therapeutic protocols could offer a holistic and cost-effective strategy for PE management, ultimately improving maternal and fetal health outcomes.
Wazib S, Ambardar Y, Quasimi H, Alam S, Afghan S, Alam MI. · Journal of Ayurveda and integrative medicine (2025)
Among these medicinal plants, Asparagus racemosus willd. (AR) (Shatavari) has gained significant attention due to its rich composition of saponins, flavonoids, and antioxidants.
These bioactive compounds play a crucial role in enhancing NO production, reducing oxidative stress, and improving endothelial function in PE.
While traditional use supports their benefits, rigorous research is needed to confirm efficacy, safety and dosage.
By addressing these issues, Asparagus racemosus may be positioned as a viable alternative or adjuvant in the treatment of AD.
Nadeem M, Khan MA, Ahmad FJ, Parvez S, Akhtar M, Najmi AK. · 3 Biotech (2025)
Moreover, thorough mechanistic research is required to elucidate its therapeutic targets and interactions due to the intricacy of its phytochemical makeup.
To improve effectiveness and bioavailability, future studies should focus on creating standardized formulations, including cutting-edge delivery methods like nanoformulations.
To confirm its therapeutic potential and safety profile in AD patients, extensive, rigorous clinical studies are necessary.
It highlights its potential as a botanical psychobiotic and proposes directions for future clinical validation within the context of postpartum mental health frameworks.
D D, Krishnarajabhatt HS, Unnikrishnan P. · Frontiers in nutrition (2025)
High-Performance Thin-Layer Chromatography (HPTLC) analyses have demonstrated that dry Shatavari contains a significantly richer concentration of bioactive phytoconstituents, such as steroidal saponins and flavonoids, compared to its wet form.
These compounds exhibit prebiotic activity, influence microbial composition, and support the modulation of neurotransmitters.
This mini review examines the intersection of phytochemical richness in dry A. racemosus and its emerging role in microbiota-mediated mood regulation.
17Psychological stress (PSS score)RCTn=35 · small study2026
Shatavari root extract oral administration can be a safe and effective potential intervention for women with PCOS.
Mhatre Y et al. · Frontiers in endocrinology (2026)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
At 12 weeks, Ovarian volume did not differ significantly between groups (p= 0.254).
SHT significantly reduced psychological stress (PSS score: -6.64 ± 3.99; p < 0.0001), decreased follicular count (p < 0.0001), and increased endometrial thickness (p = 0.028) compared to PL.
No serious adverse events occurred; mild to moderate events were reported in 11.4% (SHT) and 8.5% (PL) of participants, all manageable with standard therapy and not related to the intervention.
Ademola J, Ajgaonkar A, Debnath T, Debnath K, Langade J. · Frontiers in reproductive health (2025)
Significant improvements in MRS scores were observed in the ARE-SHT group compared to SHT [Week 4 and 8 ( p < 0.0001)] and PL [weeks 4 ( p = 0.01) and 8 ( p < 0.0001)], respectively.
Esteem-related affect ( p = 0.025) and mood improvement ( p = 0.008) showed significant changes between the groups.
Mild adverse events were reported by four participants (loose stools and dizziness in the ARE-SHT group, nausea in the SHT monotherapy group, and headache in the PL group).