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Wy3.5
Wild Yam – Forschung
Hilft vermutlich
33 begutachtete Studien
Was die Evidenz sagt
Hilft vermutlich
Wild Yam half in etwa der Hälfte (2/3) der Studien, die einen Effekt gemessen haben — vielversprechend, aber nicht einhellig.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2001–2026 mit einer typischen Studiengröße von 96 Teilnehmenden.
Basierend auf 33 Studien · 1 Meta-Analyse · 13 RCTs · 269 Teilnehmende insgesamt
Konfidenz
Mittlere Konfidenz
Was die Studien gefunden haben
2geholfen1unklar· 30 weitere ohne bewertete Effektdaten
Nach Outcome
Menopause & hormonalDie einzige RCT zu Wechseljahren fand keinen Vorteil gegenüber Placebo · 4-8 weeks · Traditionelle krampflösende Anwendung bei Krämpfen; keine Evidenz am Menschen · 1-3 cycles
Hilft vermutlich23 Studien
Therapeutic & clinical
Überwiegend Mechanismus / Beobachtung4 Studien
Cognitive function
Überwiegend Mechanismus / Beobachtung3 Studien
Bone health
Zu wenige bewertete Studien2 Studien
Heart & blood pressure
Zu wenige bewertete Studien1 Studie
Cholesterol & lipids
Zu wenige bewertete Studien1 Studie
Depression & mood
Zu wenige bewertete Studien1 Studie
Inflammation
Zu wenige bewertete Studien1 Studie
Longevity & aging
Zu wenige bewertete Studien1 Studie
In Zahlen
Aus 11 Studien mit messbaren Effekten gezogen
Untersuchte Personen
269
typische Studie: 96 Personen
Stärkste Designs
14
1 gepoolt, 13 randomisiert
Zeigte Nutzen
67%
2/3 Studien
Untersuchte Populationen
Menopausal women6
General population with hormonal conditions1
Cardiovascular disease patients1
General population1
Aktives Forschungsgebiet
15 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2023
200120132026
1Meta-Analyse2023
Wang C, Li S, Meng J, Xia M, Bo Q, Ying W · Altern Ther Health Med (2023)
2Systematische ÜbersichtCited 75×n=150 · medium study2020
Keywords related to glioma, ischemia, memory, aging, cognitive impairment, Alzheimer, Parkinson, and neurodegenerative disorders were searched in the databases based on DG and its derivatives.
Cai B et al. · Oxidative medicine and cellular longevity (2020)
Three independent researchers examined articles for eligibility.
A total of 150 articles were screened from the above scientific literature databases.
Finally, a total of 46 articles were extracted and included in this review.
The results of RCTs of the hop flavonoid 8-prenylnaringenin are conflicting.
Depypere HT et al. · Maturitas (2014)
The results of RCTs of the hop flavonoid 8-prenylnaringenin are conflicting.
Animal and human studies suggest that Dioscorea villosa (Wild yam),and Broccoli may protect against osteoporosis and breast and gynecological cancers but further evidence is required.
Linseed may protect against breast cancer but the results are conflicting.
It is noteworthy that newly synthesized DSG derivatives and DSG delivery systems have good antithrombotic activity and pharmacokinetic characteristics.
Wu FC et al. · Food & function (2019)
Numerous preclinical studies have shown that DSG has great potential in the treatment of various cardiovascular diseases in vivo and in vitro, especially in atherosclerosis.
This review mainly discusses the effects of DSG on endothelial dysfunction, lipid profile, and macrophage foam cell formation, VSMC viability, thrombosis and inflammation during the formation of atherosclerosis.
Also, the mechanism of DSG on atherosclerosis was elaborated in detail.
Future larger and better controlled studies testing the effectiveness of these treatments are needed.
Shou C et al. · Chinese journal of integrative medicine (2011)
An increased number of women seek the use of complementary and alternative medicine (CAM) for treating menopausal symptoms.
This review analyzes the evidence from systematic reviews, randomized controlled trials and epidemiological studies of using herbal medicine (Black cohosh, Dong quai, St John's wart, Hops, Wild yam, Ginseng, and evening primrose oil) and acupuncture for the treatment of menopausal symptoms.
Evidence supporting the efficacy and safety of most CAM for relief of menopausal symptoms are limited.
Selective serotonin reuptake inhibitors and venlafaxine have been shown to reduce hot flashes by 19 to 60 percent and were well tolerated by study participants.
Soy isoflavones reduced hot flashes by 9 to 40 percent in some trials, but most trials showed no difference compared with placebo.
Black cohosh and red clover also have had inconsistent results, with some trials showing benefit and some no difference compared with placebo.
16Systematische ÜbersichtCited 23×2005
A critical review of the literature shows that progesterone may have an independent effect on relieving hot flashes.
Haimov-Kochman R et al. · Acta obstetricia et gynecologica Scandinavica (2005)
A critical review of the literature shows that progesterone may have an independent effect on relieving hot flashes.
New nonhormonal agents such as selective serotonin-uptake-inhibitor anti-depressants and a new anti-convulsant gabapentin yielded promising results on small well-conducted studies.
Isoflavone's effect on hot flashes is variable and inconsistent, and only modest and delayed improvement of symptoms could be expected by BC and vitamin E.