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Wmw4.5
Wormwood – Forschung
Überwiegend Mechanismus / Beobachtung
23 begutachtete Studien
Was die Evidenz sagt
Überwiegend Mechanismus / Beobachtung
Die meisten Studien zu Wormwood sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2004–2026 mit einer typischen Studiengröße von 50 Teilnehmenden.
Basierend auf 21 Studien · 1 Meta-Analyse · 14 RCTs · 50 Teilnehmende insgesamt
Konfidenz
Mittlere Konfidenz
Nach Outcome
Digestive healthTraditionelle Anregung der Verdauung durch Bitterstoff-Tonikum; moderne Humandaten sind begrenzt und indirekt · Akut (Bitterstoff-Wirkung); Wochen für entzündliche Endpunkte
Zu wenige bewertete Studien2 Studien
InflammationZwei kleine Studien zu Morbus Crohn zeigten steroidsparende Effekte und eine Senkung von TNF-alpha — vielversprechend, aber sehr klein und nicht repliziert · 6-8 Wochen (in den Crohn-Studien)
Zu wenige bewertete Studien1 Studie
Safety profile
Zu wenige bewertete Studien1 Studie
Aktives Forschungsgebiet
9 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2021
200420152026
1Meta-Analyse2021
Sasani N, Kazemi A, Rezaiyan M, Amiri-Ardekani E, Akhlaghi M, Babajafari S · Int J Clin Pract (2021)
Einfach gesagt: This study highlights A. annua's traditional use and contemporary pharmacological research, bringing unique insights into the usage of A. annua in the treating a wide range of ailments.
Einfach gesagt: The insights provided here aim to inspire innovation in the utilization of Artemisia as a transformative botanical resource for health, industry, and sustainability.
Selim S, Harun-Ur-Rashid M, Al Jaouni SK. · Journal of pharmaceutical analysis (2026)
Furthermore, Artemisia 's contributions to sustainable agriculture, functional foods, and cosmeceuticals underline its adaptability and economic significance.
However, gaps in clinical validation, sustainable cultivation, and regulatory frameworks remain barriers to fully harnessing its potential.
Future multidisciplinary research and ethical policies are essential to integrate Artemisia more effectively into global health and industry.
Einfach gesagt: This underscores the need for further exploration of its therapeutic potential.
Cheng FE, Zhang X, Zou X, Zhang Y, Qi W, Zheng S, Li S, Wang Q, Ye Y, Zao X. · Journal of ethnopharmacology (2025)
These compounds inhibit cancer cell proliferation, invasion, and metastasis, and induce apoptosis by regulating pathways like PI3K/AKT, JAK-STAT, p53, and GPX4.
They also modulate the immune and tumor microenvironment, enhancing chemotherapeutic drug efficacy.
Conclusion The active ingredients of Artemisia annua L. show great potential for cancer treatment, highlighting its broad applications and clinical value.
Einfach gesagt: These results demonstrate that AA compounds have significant potential as adjuncts or alternatives in cancer management and warrant rigorous evaluation in standardized clinical trials.
Abdulsamad M, Musa EB, Miftah E. · Open veterinary journal (2026)
Among the included studies, six of seven eligible studies (86%) reported measurable reductions in tumor size or volume, and four documented apoptosis induction.
So far, the possibility of dose- or regimen-dependent toxicities reported elsewhere in the literature is not excluded; however, further comprehensive studies are needed to confirm this.
This review is the first to consolidate recent preclinical evidence highlighting ferroptosis as one of the key mechanisms of AA derivatives, thereby expanding the understanding of their multifaceted anticancer activity.
Einfach gesagt: Conclusions Coseasonal initiating Artemisia annua SLIT demonstrated clinical efficacy and safety for children and adult patients with ARC.
Li J, Liu W, Xu YJ, Fu Q, Liu J. · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2025)
Compared with the baseline, the levels of total rhinoconjunctivitis symptom score (TRSS), total medication score (TMS), and combined symptom and medication score for rhinoconjunctivitis (CSMS-RC) experienced significant reductions after 1 year SLIT.
Additionally, these outcomes also decreased significantly in SLIT group when compared with the control group during 2023 pollen season.
Especially, there were more patients showed symptoms reduction, medication use decrease, and efficacy improvement in the SLIT group.