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Ym3.5
Yerba Mate – Forschung
Überwiegend Mechanismus / Beobachtung
32 begutachtete Studien
Was die Evidenz sagt
Überwiegend Mechanismus / Beobachtung
Die meisten Studien zu Yerba Mate sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2014–2026 mit einer typischen Studiengröße von 92 Teilnehmenden.
Basierend auf 32 Studien · 5 Meta-Analysen · 7 RCTs · 411,350 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Nach Outcome
Weight managementGeringe Reduktionen der Körperfettmasse und des Taille-Hüft-Verhältnisses in einer 12-wöchigen RCT; eine Meta-Analyse bewertete die Effekte auf Gewicht/BMI als 'begrenzt' · 8-12 Wochen
Überwiegend Mechanismus / Beobachtung4 Studien
Safety profile
Zu wenige bewertete Studien2 Studien
Aktives Forschungsgebiet
28 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2026
201420202026
1Systematische Übersicht2026
Culturally sensitive, dermatology-focused prevention can help reduce OSCC incidence and disparities while respecting community identity.
Nowak NC, Forsyth A, Blan B, Ambardekar SS, Frasier K, Werpachowski N, Mansini AP. · Oncoscience (2026)
This narrative review combines epidemiological, mechanistic, and public health evidence on cultural carcinogens in OSCC, emphasizing prevention strategies that honor cultural identity through education, harm reduction, and community involvement.
Dermatologists specializing in mucocutaneous oncology can detect early lesions like leukoplakia, erythroplakia, and oral submucous fibrosis.
Including oral mucosal screening in routine care provides an effective, affordable way to prevent diseases in high-risk populations.
In conclusion, YM represents a promising source of functional ingredients with broad potential for health-oriented and culinary applications.
Zhang C, Chen J, Ruan S, Wang Z, Dai X. · Critical reviews in food science and nutrition (2026)
Evidence supports several health benefits of YM, including anti-inflammatory, antioxidant, anti-obesity, and cardioprotective properties, along with potential prebiotic effects.
However, safety concerns exist, particularly the possible formation of polycyclic aromatic hydrocarbons (PAHs) during traditional drying processes.
Beyond its use as a beverage, YM shows strong potential in the food industry for applications in functional foods, nutraceuticals, and natural preservatives.
Considering climate change as a stressor is likely to provide a valuable conceptual framework within which its effects can be studied.
Vasudeva R, Tregenza T, Hosken DJ. · Current opinion in insect science (2026)
We review the potential effects of rising temperatures on mate choice in insects.
We suggest that there are multiple ways temperature increases could affect mate choice and preference-trait correlations, but the detail and significance of these effects will vary across taxa.
Increased temperatures are likely to be stressful and hence to impact condition with knock-on effects for mate choice.
Conclusions Release of sterile wolbachia-infected male A. aegypti mosquitoes reduced vector populations and the risk of dengue infection in Singapore. (Funded by the Singapore Ministry of Finance and others; ClinicalTrials.gov number, NCT05505682.).
Lim JT, Chong CS, Chang CC, Mailepessov D, Dickens B, Lai YL, Deng L, Lee C, Tan LY, Chain G, Zulkifli MF, Liew JWK, Vasquez K, Chau ML, Ng Y, Lee V, Wong JCC, Sim S, Tan CH, Ng LC, Project Wolbachia–Singapore Consortium. · The New England journal of medicine (2026)
In the intention-to-treat analysis at 6 months or more, the percentage of residents in the intervention clusters who were dengue-positive was lower than that in the control clusters (354 of 5722 tests [6%] vs. 1519 of 7080 tests [21%]).
The protective efficacy of the intervention, calculated as (1 - odds ratio) × 100, ranged from 71 to 72% with 3 to 12 months or more of wolbachia mosquito exposure, as represented by odds ratios of 0.28 to 0.29.
Conclusions Release of sterile wolbachia-infected male A. aegypti mosquitoes reduced vector populations and the risk of dengue infection in Singapore. (Funded by the Singapore Ministry of Finance and others; ClinicalTrials.gov number, NCT05505682.).
The intergenerational and developmental evidence about the familiality and course of mental disorders helps to deconstruct "p" and invites psychopathology research and clinical science to reconsider their common approach to studying one mental disorder at a time. (PsycInfo Database Record
Caspi A et al. · Journal of psychopathology and clinical science (2026)
This creates a situation whereby their offspring, whether through genetic and/or environmental transmission, are at heightened risk of developing a variety of different mental disorders, but which specific disorder offspring ultimately develop is not easy to predict.
Given that offspring inherit these multiple liabilities, it may not surprise that these liabilities manifest as different disorders at different points throughout their lives, but which disorder emerges at a particular time is difficult to foretell.
The intergenerational and developmental evidence about the familiality and course of mental disorders helps to deconstruct "p" and invites psychopathology research and clinical science to reconsider their common approach to studying one mental disorder at a time. (PsycInfo Database Record
Research and development of technologies to utilize these byproducts promotes innovation and efficient use of resources, highlighting yerba mate as a renewable resource with multiple industrial applications.
Sola IMMS, Sola MBMS, Nogueira A, Alberti A. · Journal of the science of food and agriculture (2026)
These byproducts can be converted into materials such as fertilizers and sustainable packaging.
Biorefineries play a critical role in converting these residues into value-added products, such as bioplastics and nanoparticles, using a variety of technologies ranging from biological approaches to thermochemical processes.
In the food, pharmaceutical and materials industries, the extraction of bioactive compounds from yerba mate, such as chlorogenic acid and caffeine, enables their application in products ranging from biodegradable films to antioxidant additives.
This article is part of the theme issue 'Exploring negative frequency dependent selection across levels: from genetics to ecology and back again'.
Hedrick P et al. · Philosophical transactions of the Royal Society of London. Series B, Biological sciences (2026)
In and near Yellowstone National Park between 1995 and 2024, 59.3% of the matings were observed to be between wolves of different colour, while only 44.9% were expected to be.
Overall, from 1988 to 2019, 98.0% of the observed pairings were between mates with different phenotypes, while only 50% were expected.
Since then, there have been a large number of studies that have not found decreased mate sharing of HLA alleles and found mating frequencies consistent with random-mating expectations.
Together, these results demonstrate that facial-attractiveness judgements extend well beyond heterosexual mate choice and reflect the joint influence of facial structure, rater characteristics and sociocultural context.
Wassiliwizky E, Zietsch BP, Kleisner K, Ullén F. · Proceedings. Biological sciences (2026)
Morphometric analyses further show that sexual shape dimorphism accounts for a substantial portion of the GAP.
Additionally, we observe a tendency for greater stringency among male raters.
This study draws on the largest worldwide collection of facial-attractiveness data assembled to date, which we make openly available to facilitate future research.
This coordinated hormonal system may have conferred adaptive advantages by stabilizing cognition and affect during critical reproductive phases.
Carlson J et al. · Neuroscience and biobehavioral reviews (2026)
This coordinated hormonal system may have conferred adaptive advantages by stabilizing cognition and affect during critical reproductive phases.
Disruption of this balance in modern contexts may increase vulnerability to psychiatric disorders.
This model generates testable predictions and supports receptor-specific therapeutic strategies, including selective estrogen receptor modulators and neurosteroid-based interventions.
By integrating multidisciplinary knowledge, this work provides solid foundations for the scientific and technological valorization of I. paraguariensis.
Palavicini SMS, Puton BMS, Jacques RA, Valduga E, Backes GT, Paroul N, Steffens C, Cansian RL. · Journal of food science (2025)
Particular emphasis is given to studies on simulated gastrointestinal digestion, which reveal the bioaccessibility and stability of key compounds such as chlorogenic acid and caffeine.
The review also explores the wide range of technological applications of yerba mate, spanning functional foods, cosmetics, pharmaceuticals, biodegradable packaging, and international patents.
By integrating multidisciplinary knowledge, this work provides solid foundations for the scientific and technological valorization of I. paraguariensis.
Future research should include rigorously designed randomized trials and mechanistic studies using advanced human-relevant platforms, such as organoids and organ-on-chip systems.
Cassotta M, Cao Q, Hu H, Martinez CR, Dzul Lopez LA, Gracia Villar S, Battino M, Giampieri F. · Nutrients (2025)
Preclinical studies appear to indicate modulation of inflammatory and redox pathways relevant to RA.
Conclusions: Yerba mate and its constituents show preliminary indications of anti-inflammatory and antioxidant effects with potential relevance to RA pathophysiology.
However, in the absence of clinical trials in RA patients, conclusions remain tentative, constrained by small sample sizes, methodological heterogeneity, species differences, and internal validity concerns.
Almond CS, Daly KP, Albers EL, Alejos JC, Ameduri R, Auerbach SR, Barkoff L, Barnes AP, Bock MJ, Butto A, Carlo WF, Castleberry CD, Chrisant MR, Deshpande SR, Dreyer WJ, Everitt MD, Feingold B, Gonzales S, Hollander SA, Kindel SJ, Klein GL, Lal AK, Lamour JM, Lee J, Lu M, Lytrivi ID, Miyamoto SD, Pahl E, Peng DM, Ryan TD, Singh TP, Su JA, Sutcliffe DL, Ybarra AM, Zangwill S, Rossano JW, Sleeper LA, TEAMMATE Trial Investigators. · JAMA (2025)
Results Among 211 children randomized, the mean age was 8.2 (SD, 6.3) years, 97 (46%) underwent transplant for congenital heart disease, and 49 (23%) were treated for rejection before 6 months.
At 30 months, the mean MATE-3 score did not differ between the 2 treatment groups (mean difference, -0.32; 95% CI, -0.90 to 0.20; P = .16).
The mean MATE-6 score was no higher in the everolimus group than in the mycophenolate group (baseline-adjusted mean difference, -0.40; 95% CI, -1.81 to 0.93), meeting the success criterion for safety (noninferiority margin <3).
CONCLUSIONS: The low adherence underscores the necessity for TB treatment support interventions, particularly among those living with HIV.
Steulet A, Hippner P, Maraba N, Jennings L, Rabothata I, Mukora R, Xaba N, Mchunu L, Velen K, Orrell C, Charalambous S, Fielding K. · BMC infectious diseases (2026)
We used logistic regression to model poor adherence (< 80% pillbox engagement), and negative binomial regression to model adherence as a count of pillbox engagement.
RESULTS: Among 1,213 participants (nine clinics) in the control group, 61.2% (742) were male, the median age was 36 years, 63% (769) were living with HIV, with 66% (507/769) on antiretroviral therapy.
The median time to access clinical care was 127 min and 95% (1151/1213) reported no perceived stigmatization upon starting TB treatment.
Emphasizing the roles of multimodal signal-mediated sexual communication in parasitoids, this review sheds light on their integrated use and suggests implications for pest management and future research directions.
Tonğa A, Ali J, Adams B. · Journal of insect physiology (2026)
The interaction between different cues during courtship and mating is examined, highlighting how they influence reproductive behaviours and success.
Post-mating interactions are also discussed, focusing on how communication may continue to ensure maintenance of female reproductive strategies.
This review addresses the emerging field of sexual cue perception in parasitoids, emphasizing that while initial studies have only recently begun to explore underlying mechanisms, there remains a profound lack of understanding of how parasitoid nervous systems integrate multiple sensory inputs.
The current research provides insight into one set of psychological changes that may facilitate accelerated mating goals in response to environmental stressors.
Cunningham K, Mengelkoch S, Bradshaw HK, Mittal C, Hill SE. · Personality & social psychology bulletin (2026)
An internal meta-analysis of the five studies revealed adults with low CSES reported lower mate value following exposure to financial threat (relative to control).
Furthermore, lower self-perceived mate value predicted lower standards for indirect mating benefits and increased perceived compatibility with low-quality partners (Studies 2a-3).
Similar responses were not observed among individuals from high CSES environments.
16Systematische Übersichtn=11,837 · very large study2026
The results suggest that SPMV is a robust correlate of self-esteem across diverse measures and demographic groups, highlighting its relevance in understanding self-worth.
J S, Barman JD, Maheshwari S. · Journal of sex & marital therapy (2026)
The findings revealed a strong positive association between SPMV and self-esteem (r = 0.512, 95% CI = [0.467, 0.553], p < 0.001).
Meta-regression and subgroup analysis revealed that the association between the two variables is strong and consistent across various variables; hence, no significant moderating effect of gender, age, self-esteem measures, or mate value measures is found.
These findings are consistent with sociometer theory, which posits that self-esteem functions as a gauge of social acceptance and evolutionary perspectives on mate value.
Given that most Orthopteran species rely on acoustic communication for mate attraction and reproductive success, it is imperative to study the impacts of ALAN on their acoustic behavior.
Gupta K, Singh P, Sehrawat L, Diwakar S. · Journal of insect physiology (2026)
This review highlights the physiological traits affected by ALAN such as body size, developmental time, survival rate, reproductive investment, circadian rhythm, and immune response.
Behaviors affected by ALAN, such as visual orientation, locomotion, calling behavior, and mate searching, are also highlighted.
It emphasizes the critical need for targeted research on their calling behavior, the efficacy of acoustic signals, mate attraction, and reproductive success for understanding the behavioural shifts as a consequence of ALAN.
We conclude that a more satisfying account of human mating will require refined measurement of its social embeddedness, greater focus on conflict negotiation, and continued cross-cultural research.
Agey E, Conroy-Beam D, Lawson DW. · Evolutionary anthropology (2026)
However, despite ample evidence that human mate selection is uniquely shaped by others, existing research allocates outsized attention to individual preferences.
Here, we take stock of the implications of arranged marriage, highlighting measurement issues that obscure continua of parental influence and likely drive inconsistency in the downstream literature.
We conclude that a more satisfying account of human mating will require refined measurement of its social embeddedness, greater focus on conflict negotiation, and continued cross-cultural research.
Our study unifies several decades of knowledge on conspicuous traits, confirms many predictions made by the theory of sexual selection, and lays a clear path for the future of research on this topic.
Pollo P, Lagisz M, Macedo-Rego RC, Mizuno A, Yang Y, Nakagawa S. · Ecology letters (2025)
Most of these patterns are consistent across both taxa and sexes, underscoring the generalisability of our results.
Furthermore, the strength of pre-copulatory sexual selection on conspicuousness is positively associated with the relationship between (i) conspicuousness and fitness benefits and (ii) conspicuousness and individual condition.
This suggests that the relationships we assessed regarding trait conspicuousness would be stronger if we could select only traits that are truly used for mate attraction.
20Systematische Übersichtn=22 · very small study2025
Prospective studies, with a standard method of speed optimization and more detailed outcomes reporting, are necessary in order to define best practices.
Jimenez Y, Tsai C, Mrizigue F, Ahmed MM. · Future cardiology (2025)
Methods PubMed, Scopus, and the Cumulative Index to Nursing and Allied Health Literature databases were searched for: (LVAD) OR (Left Ventricular Assist Device) OR (VAD) OR (Ventricular Assist Device) AND (Speed Optimization) OR (Ramp Study) from inception to April 2025.
Results 22 studies with 749 total patients were included, 45% of whom had a Heart Mate 3.
Only 1 out of 22 studies reported all 5 outcomes, with 64% reporting 2 or fewer outcomes of interest.