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Gabrielle Lyon — muscle-centric regimen

A “muscle-centric medicine” foundation built around adequate protein (she targets ~1 g per lb ideal bodyweight) plus a short, evidence-led supplement layer — creatine, omega-3, vitamin D and a few muscle/mitochondrial extras. COI: she partners with supplement brands and runs a shop. Documented as reported, not endorsed.

GL

Dr. Gabrielle Lyon is a board-certified physician who popularized “muscle-centric medicine,” centering skeletal muscle as the organ of longevity. She is the author of Forever Strong.

Documented, not endorsed. What Gabrielle Lyon, MD reports taking (as of 2026-06) — not medical advice, not a recommendation. We sell nothing; each item links to its independently evidence-graded card.
At a glance

Aimed at (inferred from 8 mapped members)

💪 Performance & recovery 6😌 Mood & stress 3🧬 Longevity & healthspan 3🩺 General health 2

Evidence makeup

4 Strong 4 Moderate
The stack · 8 compounds

Core

  • High-quality amino-acid source toward her ~1 g/lb protein target.

    Strong 9.0no dose info
  • Muscle, strength and cognition — especially for peri/postmenopausal women and older adults.

    Strong 9.5~5 g/day (notes ~12 g discussed for brain)
  • Brain and muscle health; nearly all her patients take it.

    Strong 9.04–10 g
  • Foundational; dose to measured blood level.

    Moderate 7.5no dose info (titrate to bloodwork)
  • “Very easy to supplement for muscle and brain.”

    Strong 8.5no dose info

Situational

  • Mitochondrial turnover; strength and endurance (gut–muscle axis).

    Moderate 6.0500–1,000 mg
  • Skin, hair and nails (added to coffee).

    Moderate 6.015–25 g
  • Reach the leucine/amino-acid threshold on lower-protein meals — she advises EAAs over leucine alone.

    Moderate 6.0no dose info

“no dose info” = publicly known to take it, but no reliable dose has been stated.

“Start” adds the 8 evidence-graded compounds to your own stack to edit — gated research compounds excluded. Not an endorsement.

Synergies (1)

  • Vitamin D3 + MagnesiumMagnesium deficiency impairs vitamin D metabolism and effectiveness

Documented supplement–supplement interactions between members of this stack — not a personal interaction check. Full interaction checker →

Sources: Forever Strong & drgabriellelyon.com · Huberman Lab — Lyon episode notes

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