36 peer-reviewed studies · Evidence score: 8/10
Liang H et al. • Renal failure (2025)
Through rigorous experimental validation, our study demonstrates AS's significant clinical efficacy in managing DN.
Olasehinde TA et al. • Inflammopharmacology (2024)
The Author(s), under exclusive licence to Springer Nature Switzerland AG.
Aktaş E et al. • CNS neuroscience & therapeutics (2025)
Although levodopa is indispensable for the symptomatic management of PD, emerging evidence supports the integration of plant-derived bioactive compounds as adjunct therapies with disease-modifying potential.
Faysal M et al. • Naunyn-Schmiedeberg's archives of pharmacology (2025)
The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Gote S et al. • Inflammopharmacology (2025)
The Author(s), under exclusive licence to Springer Nature Switzerland AG.
Zhang N et al. • Current neuropharmacology (2025)
The results show some efficacy of apigenin in the treatment of AD models.
Shao G et al. • Journal of ethnopharmacology (2024)
The discovery of the beneficial effects of these natural active compounds in POL supports the idea that POL could be a promising novel candidate for the treatment and prevention of inflammation-related cancers of the digestive system.
Ahmadzadeh K et al. • Cancer medicine (2024)
Our results demonstrated that apigenin, through reducing cell viability, inducing growth inhibition, apoptosis, and cell cycle arrest, and also by decreasing the tumor size, can be considered as a possible adjuvant agent in the management of colorectal adenocarcinoma.
Singh D et al. • Critical reviews in oncology/hematology (2022)
Our analysis suggests that Apigenin has potential anticancer effects against various cancers.
Rahimi A et al. • Inflammopharmacology (2022)
Overall, our findings showed the immunomodulatory potential of apigenin as an alternative treatment for the suppression of inflammatory responses and OS in different types of lung injury diseases.
Tamer F et al. • Thrombosis and haemostasis (2022)
We furthermore discuss the implications for selected phytochemicals to interfere in thrombosis and hemostasis, indicating their possible clinical relevance.
Cao Y et al. • Pharmacological research (2021)
So the synergistic effects of flavonoids with other drugs, pharmacokinetic studies, clinical trials and the safety of flavonoids are also incorporated in the discussion.
Wang L et al. • Journal of ethnopharmacology (2020)
The heat-clearing effects of S. barbata could be attributed to its anti-inflammatory and hepatoprotective activities, whereas its detoxifying effects might be due to the anti-microbial functions of neo-clerodane diterpenoids and flavones.
Wu L et al. • Pharmacological research (2020)
The strength of all recommendations was weak.
Fischer N et al. • Phytomedicine : international journal of phytotherapy and phytopharmacology (2018)
Some secondary metabolites from plants reveal radioprotective features against cellular damage caused by irradiation.
Sanadgol N et al. • Current drug targets (2017)
Further studies with a focus on the molecular mechanisms of the protective natural compounds are needed to decrease possible side effects and to develop new medicines for MS.
Xiao Z et al. • Chinese medical journal (2013)
There are three group interventions for CCN.
Chang H et al. • Nutrients (2018)
Conclusions: The present study suggested that high intake of flavonols (such as quercetin) may reduce the risk of colon cancer, and high intake of flavones (such as apigenin) may reduce the risk of rectal cancer.
Kooti W et al. • Journal of complementary & integrative medicine (2017)
Since there are compounds such as apigenin, the celery can induce inhibitory effects on fertility in case of chronic use or high concentration.
Zargaran A et al. • Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2018)
Results supported the efficacy of chamomile oleogel as a pain relief in migraine without aura.