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Studien
Cr4.5
Chrom – Forschung
Hilft wahrscheinlich
93 begutachtete Studien
Was die Evidenz sagt
Hilft wahrscheinlich
Chrom scheint in 6 von 7 Studien mit messbaren Effekten zu helfen — die Evidenz tendiert klar ins Positive.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 1980–2026 mit einer typischen Studiengröße von 618 Teilnehmenden.
Basierend auf 93 Studien · 34 Meta-Analysen · 51 RCTs · 27,332 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
6geholfen1unklar· 86 weitere ohne bewertete Effektdaten
Nach Outcome
Glucose & metabolicBescheidene, wenig gesicherte Verbesserungen bei Nüchternglukose und HbA1c, hauptsächlich bei Typ-2-Diabetes · 6-12 Wochen · Unterstützt die Insulinsignalgebung; Nutzen ohne Diabetes gering und unsicher · 4-12 Wochen
Hilft wahrscheinlich49 Studien
Cholesterol & lipids
Überwiegend Mechanismus / Beobachtung14 Studien
Weight managementBehauptungen zu Heißhunger/Gewicht schwach; Übersichtsarbeiten finden keinen klaren Effekt auf die Körperzusammensetzung · 6-12 Wochen
Überwiegend Mechanismus / Beobachtung13 Studien
Women's health
Überwiegend Mechanismus / Beobachtung13 Studien
Inflammation
Überwiegend Mechanismus / Beobachtung12 Studien
Heart & blood pressure
Überwiegend Mechanismus / Beobachtung3 Studien
Safety profile
Zu wenige bewertete Studien2 Studien
Cognitive function
Zu wenige bewertete Studien1 Studie
In Zahlen
Aus 19 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
67%
über Studien hinweg
Untersuchte Personen
27k
typische Studie: 618 Personen
Stärkste Designs
85
34 gepoolt, 51 randomisiert
Zeigte Nutzen
86%
6/7 Studien
Untersuchte Populationen
Type 2 diabetes patients3
Women with polycystic ovary syndrome2
Type 2 diabetes mellitus patients2
Adults with type 2 diabetes1
Aktives Forschungsgebiet
33 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2026
198020032026
1PCOS symptoms improvementMeta-Analysen=5,501 · very large study2025
Einfach gesagt: Chromium, inositol, and Omega-3 were found to be beneficial for improving lipid profile.
Zhao G et al. · Reproductive biology and endocrinology : RB&E (2025)
Inositol significantly decreased total cholesterol and triglyceride levels, while curcumin was most effective in improving low-density and high-density lipoprotein cholesterol levels.
Chromium, inositol, and Omega-3 were found to be beneficial for improving lipid profile.
For improving obesity, sex hormone levels, inflammatory factors and oxidative stress indicators of PCOS patients, carnitine, chromium, and soy isoflavones are effective options, respectively.
2Body weight reductionMeta-Analysen=2,362 · very large study2023
Einfach gesagt: Carnitine was relatively effective in reducing body mass, while chromium, Omega-3, and selenium were beneficial for improving glucose metabolism.
Hu X et al. · PeerJ (2023)
The network meta-analysis showed that carnitine, inositol, and probiotics reduced body weight and body mass index (BMI) compared to placebo, and carnitine outperformed the other supplements (SUCRAs: 96.04%, 97.73%, respectively).
Omega-3 lowered fasting blood glucose (FBG) (SUCRAs: 93.53%), and chromium reduced fasting insulin (FINS) (SUCRAs: 72.90%); both were superior to placebo in improving insulin resistance index (HOMA-IR), and chromium was more effective than Omega-3 (SUCRAs: 79.99%).
Selenium was potent in raising the quantitative insulin sensitivity index (QUICKI) (SUCRAs: 87.92%).
3Fasting blood glucose reductionMeta-Analysen=14,223 · very large study2023
Einfach gesagt: Low to very low certainty evidence established chromium supplements as the most effective in reducing fasting blood glucose levels and homeostasis model assessment of insulin resistance (SUCRAs: 90...
Xia J et al. · Pharmacological research (2023)
Low to very low certainty evidence established chromium supplements as the most effective in reducing fasting blood glucose levels and homeostasis model assessment of insulin resistance (SUCRAs: 90.4% and 78.3%, respectively).
Vitamin K supplements ranked best in reducing glycated hemoglobin A1c and fasting insulin levels (SUCRAs: 97.0% and 82.3%, respectively), with moderate to very low certainty evidence.
Vanadium supplements ranked best in lowering total cholesterol levels with very low evidence certainty (SUCRAs:100%).
Einfach gesagt: The results of the current meta-analysis study might support the use of chromium supplementation for the improvement of glycemic control indices in T2DM patients.
Asbaghi O et al. · Pharmacological Research (2020)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Results revealed significant reduction in FPG (weighted mean difference (WMD): -19.00 mg/dl, 95% CI: -36.15, -1.85, P = 0.030).
Significant reductions were also seen in insulin level (WMD: -12.35 pmol/l), HbA1C (WMD: -0.71 %, 95% CI: -1.19, -0.23, P = 0.004) and HOMA-IR (WMD: -1.53).
Twenty-eight studies reported fasting plasma glucose, insulin, HbA1C and HOMA-IR as an outcome measure.
5Body weight reductionMeta-Analysen=1,316 · large study2019
Einfach gesagt: Chromium supplementation was associated with some improvements in body composition in subjects with obesity/overweight.
Tsang C et al. · Clinical Obesity (2019)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Pooled analysis showed significant reductions in anthropometric indices associated with body composition; for weight loss (weighted mean difference [WMD]: -0.75 kg, 95% confidence interval [CI], -1.04, -0.45, P < 0.001).
Body fat percentage was reduced (WMD: -0.68%, 95% CI, -1.32, -0.03, P = 0.04) in individuals with overweight/obesity.
The effect size was medium and the clinical relevance of chromium as a weight loss aid remains uncertain.
6Total antioxidant capacityMeta-Analysen=550 · large study2022
Einfach gesagt: Chromium supplementation may improve OS parameters, however, due to high heterogeneity observed in the included studies, these findings should be interpreted with caution.
Morvaridzadeh M et al. · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) (2022)
Spürbar Nutzen
← SchlechterKein EffektBesser →
The obtained results indicate that chromium supplementation significantly increases TAC (SMD: 0.46; 95 % CI: 0.08, 0.84; I2 = 00.0 % n = 2) and significantly decreases MDA levels (SMD: -0.46; 95 % CI: -0.86, -0.07; I2 = 52.4 % n = 5).
Chromium supplementation may improve OS parameters, however, due to high heterogeneity observed in the included studies, these findings should be interpreted with caution.
Large RCTs on various patient groups evaluating the impact of chromium supplementation are needed to allow an adequate generalization of the benefits of chromium on human health.