1Meta-Analysis2022
Colacci M, Fralick J, Odutayo A, Fralick M · Can J Diabetes (2022)
No plain-language summary recorded for this citation — open the paper to read its abstract.
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826 peer-reviewed studies
What the evidence says
Most Dapagliflozin studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 2009–2026 with a typical study size of 257 participants.
Based on 824 studies · 221 meta-analyses · 547 RCTs · 132,431 total participants
Confidence
High confidenceBy outcome
546 studies in the last 5 years · Latest meta-analysis: 2026
Colacci M, Fralick J, Odutayo A, Fralick M · Can J Diabetes (2022)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Fernandes JV, Ramos JV, Holanda MM · Minerva Med (2025)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Banerjee M, Pal R, Maisnam I, Chowdhury S, Mukhopadhyay S · Diabetes Obes Metab (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Zheng Z, He D, Chen J, Xie X, Lu Y, Wu B · Clin Drug Investig (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Zhang HD, Ding L, Mi LJ, Zhang AK, Zhang K, Jiang ZH · Eur J Prev Cardiol (2024)
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Wang LG, Wang H, Liu Q, Hua WC, Li CM · Biomed Pharmacother (2017)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Jhund PS, Kondo T, Butt JH, Docherty KF, Claggett BL, Desai AS · Nat Med (2022)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Ali EAH, Rabadi M, Aweer RA, Subahi E, Abdelmahmuod EA, Alshurafa A · Eur J Clin Pharmacol (2026)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Tang HL, Li DD, Zhang JJ, Hsu YH, Wang TS, Zhai SD · Diabetes Obes Metab (2016)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Musso G, Gambino R, Cassader M, Pagano G · Ann Med (2012)
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Adamou A, Chlorogiannis DD, Kyriakoulis IG, Stamatiou I, Koukousaki D, Kardoutsos I · Intern Emerg Med (2024)
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Langford BE, Evans M, Haskins-Coulter T, O'Connor M, Cant HEO, Eddowes LA · Diabetes Obes Metab (2020)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Tsai PC, Chuang WJ, Ko AM, Chen JS, Chiu CH, Chen CH · Cardiovasc Diabetol (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Ida S, Kaneko R, Imataka K, Okubo K, Shirakura Y, Azuma K · Curr Diabetes Rev (2021)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Tomasoni D, Adamo M, Lombardi CM, Metra M · ESC Heart Fail (2019)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Meng Z, Wu H, Miao Y, Qi W, Sha M · Front Endocrinol (Lausanne) (2026)
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Tong X, Song X, Zhang Y, Zhao Q · Arch Physiol Biochem (2024)
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Zheng Y, Sun J · Medicine (Baltimore) (2025)
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Li D, Liu Y, Hidru TH, Yang X, Wang Y, Chen C · Front Endocrinol (Lausanne) (2021)
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Fadini GP, Li Volsi P, Devangelio E, Poli M, Cazzetta G, Felace G · J Endocrinol Invest (2020)
No plain-language summary recorded for this citation — open the paper to read its abstract.