48 peer-reviewed studies · Evidence score: 8.5/10
Morze J et al. • Diabetes care (2022)
Several plasma and serum metabolites, including amino acids, lipids, and carbohydrates, are associated with type 2 diabetes risk.
Huang X et al. • PloS one (2024)
Our results confirm the adverse effects of ICP on co-existing pregnancy complications, obstetric and neonatal outcomes.
Guasch-Ferré M et al. • Diabetes care (2016)
In studies using high-throughput metabolomics, several blood amino acids appear to be consistently associated with the risk of developing type 2 diabetes.
Chang CH et al. • Journal of psychopharmacology (Oxford, England) (2020)
The meta-analysis suggests that sarcosine may be associated with treatment effect on overall clinical symptoms in patients with schizophrenia but not cognitive functions.
Cancelo-Hidalgo MJ et al. • Current medical research and opinion (2013)
Extended-release ferrous sulfate with mucoproteose appears to be the best tolerated of the different oral iron supplements evaluated.
Soh J et al. • GeroScience (2024)
This systematic-review examined the effects of Glycine.
Lau KT et al. • Current osteoporosis reports (2023)
On the other hand, given that metabolomics could be affected by genetics and environmental factors, whether the inconsistent association of the metabolites with BMD is due to the interaction between metabolites and genes and/or lifestyle warrants further study.
Soares C et al. • Molecular psychiatry (2024)
The Author(s), under exclusive licence to Springer Nature Limited.
Song L et al. • Archives of medical research (2024)
This study identified histidine, methionine, asparagine, hypoxanthine, and glycine as significantly correlated with RA, thus offering the potential for the advancement of biomarker discovery and the elucidation of disease mechanisms in RA.
Chuchueva N et al. • Metabolomics : Official journal of the Metabolomic Society (2023)
The present work highlights utility of metabolite-based biomarkers for risk assessment, early detection, and prognostication of HNC, as well as facilitates incorporation of available metabolomics studies into multi-omics data integration and big data analytics for personalized health.
Mielgo-Ayuso J et al. • Nutrients (2021)
However, chronic or acute l-C or GPL-C supplementation did not present improvements on moderate exercise performance.
Razavi SA et al. • Cancer medicine (2024)
It appears that the field of TC metabolomics will experience notable advancement, leading to the discovery of trustworthy diagnostic and prognostic biomarkers.
Xu M et al. • Diabetes care (2022)
Our study identified the causal roles of SGLT2 inhibition in choline metabolites.
Błaszczuk A et al. • Nutrients (2022)
This meta-analysis provides evidence that consuming flaxseed, soy and red clover can have a beneficial effect on lipids in postmenopausal women and suggest a favorable effect in preventing cardiovascular diseases.
Badenoch J et al. • Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2021)
Tics were most commonly reported in the post-encephalitic period and involvement of the basal ganglia was frequently observed.
Clardy SL et al. • JAMA neurology (2013)
Childhood-onset SMS is a rare but underrecognized and treatable disorder.
Sun Y et al. • The Journal of clinical endocrinology and metabolism (2020)
Several metabolites and metabolic pathways associated with T2D have been identified, which provide valuable biomarkers and novel targets for prevention and drug therapy.
Lin YC et al. • International journal of molecular sciences (2026)
We also highlight the potential of these two miRNAs as biomarkers and therapeutic targets for HCC and MAFLD, discussing emerging strategies such as antisense-based inhibition, gene therapy, and small-molecule inducers aimed at restoring GNMT expression.
Zhu Z et al. • The American journal of clinical nutrition (2023)
Increased glutamic acid, aspartic acid, and gamma-aminobutyric acid and decreased glycine in plasma are associated with adverse outcomes after ischemic stroke, suggesting that plasma amino acid neurotransmitters may be potential intervention targets for improving prognosis of ischemic stroke.
Tuominen HJ et al. • The Cochrane database of systematic reviews (2006)
In general, all glutamatergic drugs appeared to be ineffective in further reducing positive symptoms of the disease when added to the existing antipsychotic treatment.