45 peer-reviewed studies · Evidence score: 7.5/10
Goudarzi MA et al. • Current drug targets (2024)
Our study suggests that grape products intake may help to decrease body weight in obese participants.
Martinez-Zapata MJ et al. • The Cochrane database of systematic reviews (2020)
There is moderate-certainty evidence that phlebotonics probably reduce oedema slightly, compared to placebo; moderate-certainty evidence of little or no difference in QoL; and low-certainty evidence that these drugs do not influence ulcer healing.
Petrelli F et al. • Head & neck (2022)
In conclusion, in patients with HPV+ OPC, de-escalation treatments should not be widely and agnostically adopted in clinical practice, as therein lies a concrete risk of offering a sub-optimal treatment to patients.
Mao Y et al. • World journal of surgical oncology (2022)
These results suggest that cytoreductive prostatectomy can confer survival benefits to OPC patients.
Sarkhosh-Khorasani S et al. • The British journal of nutrition (2021)
Further well-designed and long-term clinical trials are highly recommended to achieve more comprehensive and accurate results.
Fu Z et al. • The Journal of nutrition (2017)
This trial was registered at crd.york.ac.uk/prospero as CRD42015024439.
Zhang H et al. • Phytomedicine (2020)
Grape seed extract significantly reduced systolic and diastolic blood pressure compared to placebo across pooled RCTs.
Abdulla SA et al. • Clinical and experimental dental research (2025)
Antioxidants, particularly melatonin and propolis, enhance periodontal and glycemic outcomes in T2D-periodontitis patients.
GBD 2019 Lip, Oral, and Pharyngeal Cancer Collaborators et al. • JAMA oncology (2023)
In this systematic analysis, disparities in LOC and OPC burden existed across the SDI spectrum, and a considerable percentage of burden was attributable to tobacco and alcohol use.
Cui M et al. • Archives of oral biology (2024)
HPV genotyping (16, 18, 33, 35, 58) is a key factor in the prevention and treatment of OPC.
DeMers AC et al. • PloS one (2024)
Our meta-analysis does not support an overall pattern of greater complexity in herbivores than faunivores across terrestrial amniotes.
García-Manríquez N et al. • Nutrition reviews (2024)
Within the limitations of this systematic review and metaanalysis, GSE and cranberries or their active compounds could represent an alternative for caries management.
Vani NV et al. • JCO global oncology (2024)
The HPV-attributable fraction is considerably lower for OC, suggesting a negligible causative role of HPV in OC.
Tan D et al. • Journal of medical imaging and radiation oncology (2023)
Delta-radiomics-based models were found to be promising predictors of predefined end points.
Zhang H et al. • Journal of the American Dietetic Association (2011)
GSE significantly reduced systolic blood pressure.
Ribeiro-Rotta RF et al. • PloS one (2022)
The economic burden of oral cancer is substantial, though underestimated.
Panchal H et al. • Advances in nutrition (Bethesda, Md.) (2019)
Adequately powered RCTs are needed to confirm the nutritional and immunomodulatory benefits of OPC in preterm infants.Copyright © American Society for Nutrition 2019.
Asbaghi O et al. • Phytotherapy research : PTR (2020)
This meta-analysis demonstrated that GSE intake significantly reduced FPG, TC, LDL cholesterol, triglycerides, and CRP levels.
Liu M et al. • Obesity facts (2020)
This systematic-review examined the effects of Grape Seed Extract.
Delimont NM et al. • Nutrition and health (2020)
Caries prevention by grape seed extract may be unique compared with fluoride, and is linked to grape seed extract's bacteriostatic and collagen crosslinking properties.