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Snr5.5
Stinging Nettle Root – Forschung
Hilft wahrscheinlich
43 begutachtete Studien
Was die Evidenz sagt
Hilft wahrscheinlich
Stinging Nettle Root scheint in 5 von 5 Studien mit messbaren Effekten zu helfen — die Evidenz tendiert klar ins Positive.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 1990–2026 mit einer typischen Studiengröße von 72 Teilnehmenden.
Basierend auf 43 Studien · 3 Meta-Analysen · 22 RCTs · 4,191 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
5geholfen· 38 weitere ohne bewertete Effektdaten
Nach Outcome
BPH & lower urinary tract symptoms
Hilft wahrscheinlich33 Studien
Glucose & metabolic
Überwiegend Mechanismus / Beobachtung10 Studien
InflammationHemmt die entzündlichen COX- und LOX-Signalwege · 4-8 weeks
Überwiegend Mechanismus / Beobachtung6 Studien
Women's healthKann bei der Bewältigung von Wechseljahrsbeschwerden wie Hitzewallungen und Stimmungsschwankungen helfen · 4-8 weeks
Überwiegend Mechanismus / Beobachtung5 Studien
Therapeutic & clinical
Überwiegend Mechanismus / Beobachtung4 Studien
Heart & blood pressure
Überwiegend Mechanismus / Beobachtung3 Studien
Joint pain & arthritis
Zu wenige bewertete Studien2 Studien
Safety profile
Zu wenige bewertete Studien2 Studien
Men's vitalityBindet SHBG, um den Spiegel von freiem Testosteron und Östrogen zu modulieren · 4-8 weeks · Unterstützt einen gesunden Östrogenstoffwechsel und das hormonelle Gleichgewicht · 4-8 weeks
Zu wenige bewertete Studien1 Studie
In Zahlen
Aus 19 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
80%
über Studien hinweg
Untersuchte Personen
4,191
typische Studie: 72 Personen
Stärkste Designs
25
3 gepoolt, 22 randomisiert
Zeigte Nutzen
100%
5/5 Studien
Wie lange Studien liefen
1–4 Wochen
1
1–3 Monate
5
3+ Monate
1
Untersuchte Populationen
Diabetes patients2
Various populations1
Chronic tinnitus patients1
Men with LUTS suggestive of BPH1
Aktives Forschungsgebiet
18 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2022
199020082026
1Meta-Analyse2020
Ziaei R, Foshati S, Hadi A, Kermani MAH, Ghavami A, Clark CCT · Phytother Res (2020)
Einfach gesagt: However, efficacy and safety of the most plants used in the treatment of diabetes are not sufficient.
Rashidi AA et al. · Pakistan journal of biological sciences : PJBS (2013)
The quality of Randomized Controlled Trials (RCTs) assessed by using the Jadad scale.
Among the RCTs studies, the best results in glycemic control was found in Aloe vera, Citrullus colocynthus, Plantago ovata, Silybum marianum, Rheum ribes and Urtica dioica.
The majority of plants that have been studied for antidiabetic activity showed promising results.
Einfach gesagt: Further investigations are required to confirm the safety and efficacy of these compounds.
Nirumand MC et al. · International journal of molecular sciences (2018)
The main underlying mechanisms of these dietary plants and their isolated phytonutrients in the management of urolithiasis include diuretic, antispasmodic, and antioxidant activity, as well as an inhibitory effect on crystallization, nucleation, and aggregation of crystals.
The results as presented in this review demonstrate the promising role of dietary plants and phytophenols in the prevention and management of kidney stones.
Further investigations are required to confirm the safety and efficacy of these compounds.
Einfach gesagt: In conclusion, it is advisable to conduct further studies with more homogeneous population and larger number of subjects by avoiding the heterogeneity of the herbal preparations considered.
Di Lorenzo C et al. · Critical reviews in food science and nutrition (2013)
The bibliographic search found no paper regarding the anti-inflammatory effects of Calendula officinalis L. and Symphytum officinalis L. by oral use.
In spite of the long-term traditional use for inflammatory disorders, Curcuma longa L. and Harpagophytum procumbens L. warrant further investigation, whereas the efficacy of Urtica dioica L, even if the available data on hard endpoints are promising, requires other trials.
Boswellia serrata Roxb. was found to be the most promising, since it shows the best efficacy for the treatment of pain/inflammatory conditions.
6Systematische Übersichtn=12 · very small study2018
Einfach gesagt: Although just few plants have been proven to be effective for treatment of menstrual irregularities, the results and the classification in present study can be used as an outline for future studies and treatment.
Moini Jazani A et al. · BioMed research international (2018)
Einfach gesagt: We present a critical assessment of the results obtained from in vitro and in vivo studies as well as clinical trials to highlight the gaps that require further exploration for future prospective studies.
Abi Sleiman M, Younes M, Hajj R, Salameh T, Abi Rached S, Abi Younes R, Daoud L, Doumiati JL, Frem F, Ishak R, Medawar C, Naim HY, Rizk S. · International journal of molecular sciences (2024)
We further highlight the systemic protective effects of UD on the liver, reproductive, excretory, cardiovascular, nervous, and digestive systems.
We present a critical assessment of the results obtained from in vitro and in vivo studies as well as clinical trials to highlight the gaps that require further exploration for future prospective studies.
Einfach gesagt: High-quality future research, such as human large-scale trials, would be emphasized; improvement in the clinical validity of a drug might come from improved study design, better selection of potentially usable biomarkers, and enhanced safety profiles to guarantee efficacy with lessened risks.
Roy D, Ghosh M, Rangra NK. · Phytotherapy research : PTR (2025)
Great emphasis is laid on the integration of multi-omics technologies such as genomics, proteomics, metabolomics, and transcriptomics in the discovery of bioactive compounds.
The nature of the technologies can evaluate the intrinsic complexities of herbal pharmacology and even identify therapeutic candidates.
Finally, the review refers to the meagre clinical trials on the efficiency of these compounds in the metabolism of humans.
Einfach gesagt: This study aimed to collect all available knowledge about this plant, its chemical composition, and biological activity and to summarize this knowledge with particular attention to polyphenolic compounds and the activity and mechanisms of their actions.
Đurović S, Kojić I, Radić D, Smyatskaya YA, Bazarnova JG, Filip S, Tosti T. · International journal of molecular sciences (2024)
Previously conducted studies found phenolic acids and polyphenolic compounds in root, stalk, and stinging nettle leaves.
Different extraction techniques were usually used to isolate them from the leaves.
Obtained extracts were used to investigate biological activity further or formulate different functional food products.
Einfach gesagt: Nettle may safely improve glycemic control in type 2 diabetic patients needing insulin therapy.
Kianbakht S et al. · Clinical laboratory (2013)
At the endpoint, the extract lowered the blood levels of fasting glucose, 2 hours postprandial glucose, and HbA1c significantly (p < 0.001, p = 0.009, and p = 0.006, respectively) without any significant effects on the other parameters (p > 0.05) compared with placebo.
Nettle may safely improve glycemic control in type 2 diabetic patients needing insulin therapy.
Einfach gesagt: Considering the effectiveness of cumin and nettle drops in increasing milk and the availability of these native plants in Iran, it is suggested that they, especially cumin, be used postpartum to increase breast milk production.
Farshad F et al. · Sultan Qaboos University medical journal (2024)
At the beginning of the trial, no statistically significant differences were observed between the 3 groups for infant weight (P = 0.891), breastfeeding frequency (P = 0.921), number of wet diapers (P = 0.783), diaper weight (P = 0.841) and frequency of infant defecation (P = 0.898).
Considering the effectiveness of cumin and nettle drops in increasing milk and the availability of these native plants in Iran, it is suggested that they, especially cumin, be used postpartum to increase breast milk production.
Einfach gesagt: A 3-month treatment with Neurotec capsules in addition to patient education is of benefit for managing symptoms in patients with chronic tinnitus.
Khosravi MH et al. · Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery (2023)
A 3-month treatment with Neurotec capsules in addition to patient education is of benefit for managing symptoms in patients with chronic tinnitus.
18Nocturnal voiding frequency improvementMeta-Analysen=922 · large study2014
Einfach gesagt: PRO 160/120 significantly improved nocturnal voiding frequency compared to placebo and similar to tamsulosin or finasteride.
Oelke M et al. · World journal of urology (2014)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
In the pooled analysis of placebo-controlled trials, nocturnal voids improved by 0.8 (29 %) with PRO 160/120 compared to 0.6 (18 %) with placebo (p = 0.015, Wilcoxon test, one-tailed).
The 69 % responder rate to PRO 160/120 was significantly superior to the placebo response (52 %; p = 0.003, χ (2)-test, two-tailed).
PRO 160/120 significantly improved nocturnal voiding frequency compared to placebo and similar to tamsulosin or finasteride.