We use essential cookies (authentication, your saved goals/stack) by default. With your permission we’ll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more about cookies
Zc6.0
Zinc Carnosine Research
Likely helps
45 peer-reviewed studies
What the evidence says
Likely helps
Zinc Carnosine appears to help in 7 of 9 studies with measurable effects — the evidence leans clearly favourable.
Most evidence is from high-quality meta-analyses and randomised trials published 1998–2026 with a typical study size of 79 participants.
Based on 45 studies · 7 meta-analyses · 29 RCTs · 275,524 total participants
Confidence
High confidence
What the studies found
7helped1unclear1didn't help· 36 more without graded effect data
By outcome
Wound & ulcer healing
Likely helps34 studies
Gut barrier & GIImproved gut lining integrity and reduced stomach discomfort within 4-8 weeks · 4-8 weeks
Likely helps32 studies
Therapeutic & clinical
Mostly mechanism / observational10 studies
Safety profile
Mostly mechanism / observational5 studies
By the numbers
Pulled from 20 studies with measurable effects
Likely real effects
100%
across studies
People studied
276k
typical study: 79 people
Strongest designs
36
7 pooled, 29 randomised
Showed benefit
78%
7/9 studies
How long studies ran
1–4 weeks
2
1–3 months
3
3+ months
1
Populations Studied
Patients with H. pylori infection2
Patients with pressure ulcers2
Patients with gastric ulcers and H. pylori infection1
patients with NSAID-induced gastropathy1
Active research area
14 studies in the last 5 years · Latest meta-analysis: 2026
199820122026
1Meta-Analysis2023
Sureshkumar K, Durairaj M, Srinivasan K, Goh KW, Undela K, Mahalingam VT · Front Biosci (Landmark Ed) (2023)
3H. pylori eradication rateMeta-Analysisn=396 · medium study2022
In plain English: However, the evidence is still scarce, and larger trials are needed to confirm or refute our findings.
Mahmoud A et al. · Nutrients (2022)
Huge harm
← WorseNo effectBetter →
Likely real
We used the odds ratio (OR) for dichotomous outcomes presented with the corresponding 95% confidence interval (CI).
Pooled OR found a statistical difference favoring the PZN arm in the intention to treat and per protocol H. pylori eradication rates (OR: 2.01 with 95% CI [1.27, 3.21], p = 0.003) and (OR: 2.65 with 95% CI [1.55, 4.54], p = 0.0004), respectively.
We found no statistical difference between the two groups regarding the total adverse events (OR: 1.06 with 95% CI [0.55, 2.06], p = 0.85).
20Bioequivalence of polaprezinc formulationsCrossovern=24 · very small study2025
In plain English: The generic and original polaprezinc granules were bioequivalent by pharmacokinetic comparisons in healthy Chinese subjects under fasting and fed conditions.
Xiao M et al. · Clinical and translational science (2025)
The geometric mean ratios (GMR) in primary PK endpoints between the test and reference products with 90% confidence intervals (CI) were calculated.
All 90% CIs of GMRs in Cmax, AUC0-t and AUC0-∞ between the two products were within 80.0%-125.0%.
The generic and original polaprezinc granules were bioequivalent by pharmacokinetic comparisons in healthy Chinese subjects under fasting and fed conditions.