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Head-to-head evidence comparison — which supplement is right for you?
Aged Garlic Extract vs Omega-3: they're closely matched on evidence (7.5 vs 9/10); they're alternatives for reduce inflammation — the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Aged Garlic Extract and Omega-3 are closely matched across evidence, studies, and safety.
Verdict
Likely helps
14 of 15 studies with measurable effects showed benefit.
Top outcomes
Verdict
Probably helps
18 of 27 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (2)
Outcomes where both Aged Garlic Extract and Omega-3 have evidence — compare verdict strength side-by-side.
600-1200mg aged garlic extract
With meals, Split into 2 doses
Kyolic Aged Garlic Extract (most studied)
2-3g combined EPA+DHA daily
With meals containing fat
Triglyceride form fish oil
8-12 weeks
12+ weeks
4-8 weeks
4-8 weeks
2-4 weeks
Immediate
4-12 weeks
Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials
Prostaglandins & other lipid mediators (2024) · Meta analysis · n=584
AGE tea supplementation reduces systolic blood pressure (SBP) (WMD: -4.03; %95CI: -6.87, -1.20; I2: 57.1 %) and diastolic blood pressure (DBP) (WMD: -1.44; 95 % CI= -2.87, -0.02; P = 0.052; I2: 36.8 %; P: 0.105).
Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis
Phytotherapy research : PTR (2023) · Meta analysis
The standardized mean difference with 95% CI was calculated using fixed-effect or random-effect models.
A meta-analysis of randomized, double-blind, placebo-controlled trials for the effects of garlic on serum lipid profiles
Journal of the science of food and agriculture (2012) · Meta analysis · n=26
Compared with the placebo groups, serum TC and TG levels in the garlic group were reduced by 0.28 (95% CI, -0.45, -0.11) mmol L⁻¹ (P = 0.001) and 0.13 (95% CI, -0.20, -0.06) mmol L⁻¹ (P < 0.001), respectively.
Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer
The New England journal of medicine (2019) · Rct · n=25871
During a median follow-up of 5.3 years, a major cardiovascular event occurred in 386 participants in the n-3 group and in 419 in the placebo group (hazard ratio, 0.92; 95% confidence interval [CI], 0.80 to 1.06; P=0.24).
Omega-3 fatty acids for intermittent claudication
The Cochrane database of systematic reviews (2024) · Meta analysis · n=1830
Omega-3 compared with a control may have little to no effect on ankle-brachial index (MD -0.02, 95% CI -0.08 to 0.04; 3 studies, 168 participants; very low-certainty evidence).
A systematic review and meta-analysis of the omega-3 fatty acids effects on brain-derived neurotrophic factor (BDNF)
Nutritional neuroscience (2024) · Meta analysis · n=587
The present systematic review and meta-analysis indicate the efficacy of omega-3 FAs in increasing the serum concentration of BDNF.
Meta-analysis shows modest SBP reduction of ~4 mmHg and DBP reduction of ~1.4 mmHg. Effect size is relatively small compared to pharmaceutical interventions. Studies primarily used aged garlic extract forms.
Based on multiple meta-analyses showing EPA-dominant formulas >1g/day most effective. Effects plateau around 2-2.5g. Adjunctive use with antidepressants shows better outcomes than monotherapy.
AI-estimated from published studies. Interpret as directional guidance.
Both Aged Garlic Extract and Omega-3 are closely matched — the best choice depends on your specific health goals.
Both Aged Garlic Extract and Omega-3 score equally (90) for reduce inflammation.
No known interactions between Aged Garlic Extract and Omega-3 have been documented in our database. However, always consult a healthcare provider before combining supplements.
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The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.