Loading…
We use essential cookies (authentication, your saved goals/stack) by default. With your permission we'll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more
Head-to-head evidence comparison — which supplement is right for you?
Aged Garlic Extract wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
13 of 14 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
16 of 16 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (2)
Outcomes where both Aged Garlic Extract and Policosanol have evidence — compare verdict strength side-by-side.
600-1200mg aged garlic extract
With meals, Split into 2 doses
Kyolic Aged Garlic Extract (most studied)
10-20mg daily
Evening (cholesterol synthesis peaks at night), With dinner
Sugar cane-derived policosanol
8-12 weeks
12+ weeks
4-8 weeks
8-12 weeks
4-8 weeks
N/A
Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials
Prostaglandins & other lipid mediators (2024) · Meta analysis · n=584
AGE tea supplementation reduces systolic blood pressure (SBP) (WMD: -4.03; %95CI: -6.87, -1.20; I2: 57.1 %) and diastolic blood pressure (DBP) (WMD: -1.44; 95 % CI= -2.87, -0.02; P = 0.052; I2: 36.8 %; P: 0.105).
Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis
Phytotherapy research : PTR (2023) · Meta analysis
The standardized mean difference with 95% CI was calculated using fixed-effect or random-effect models.
A meta-analysis of randomized, double-blind, placebo-controlled trials for the effects of garlic on serum lipid profiles
Journal of the science of food and agriculture (2012) · Meta analysis · n=26
Compared with the placebo groups, serum TC and TG levels in the garlic group were reduced by 0.28 (95% CI, -0.45, -0.11) mmol L⁻¹ (P = 0.001) and 0.13 (95% CI, -0.20, -0.06) mmol L⁻¹ (P < 0.001), respectively.
The effects of policosanol supplementation on blood glucose: A systematic review and dose-response meta-analysis of randomized controlled trials
Diabetes research and clinical practice (2024) · Meta analysis · n=2680
To assess the effects of policosanol on glucose, we employed a random-effects or fixed-effects meta-analysis approach to examine the weighted mean differences (WMDs) and associated 95 % confidence intervals (CI) before and after policosanol and placebo administration.
What is the influence of policosanol supplementation on liver enzymes? A systematic review and dose-response meta-analysis of randomized controlled trials
Complementary therapies in medicine (2024) · Meta analysis · n=2535
The combination of effect sizes, regarding the random-effects model, demonstrated significant changes in ALT serum levels after intervention (WMD: -1.48 U/L; 95% CI: -2.33 to -0.64; P = 0.001), and AST (WMD: -1.10 U/L; 95% CI: -1.70 to -0.51; P < 0.001).
Impact of Diet on Plasma Lipids in Individuals with Heterozygous Familial Hypercholesterolemia: A Systematic Review of Randomized Controlled Nutritional Studies
Nutrients (2021) · Systematic review · n=837
A significant reduction in LDL-C levels was reported in 10 RCTs, including eight dietary supplement interventions (phytosterols, n = 6, omega-3, n = 1; guar gum, n = 1), one food-based intervention and one dietary counseling intervention.
Meta-analysis shows modest SBP reduction of ~4 mmHg and DBP reduction of ~1.4 mmHg. Effect size is relatively small compared to pharmaceutical interventions. Studies primarily used aged garlic extract forms.
Effects highly inconsistent across studies with 80% showing mixed results. Cuban studies show better outcomes than non-Cuban studies. One large RCT (n=143) found no significant LDL reduction versus placebo. Only modest effects supported when present.
AI-estimated from published studies. Interpret as directional guidance.
Aged Garlic Extract has a higher evidence score (9/10 vs 7.5/10) and wins in 2 of 3 categories.
For reduce inflammation, Aged Garlic Extract has a higher relevance score (90 vs 55).
No known interactions between Aged Garlic Extract and Policosanol have been documented in our database. However, always consult a healthcare provider before combining supplements.