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Head-to-head evidence comparison — which supplement is right for you?
Aged Garlic Extract wins 1 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
13 of 14 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
6 of 8 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Aged Garlic Extract and Saw Palmetto have evidence — compare verdict strength side-by-side.
600-1200mg aged garlic extract
With meals, Split into 2 doses
Kyolic Aged Garlic Extract (most studied)
320mg standardized extract (85-95% fatty acids)
With meals
Liposterolic extract (standardized to 85-95% fatty acids)
8-12 weeks
12+ weeks
4-8 weeks
4-12 weeks
4-12 weeks
Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials
Prostaglandins & other lipid mediators (2024) · Meta analysis · n=584
AGE tea supplementation reduces systolic blood pressure (SBP) (WMD: -4.03; %95CI: -6.87, -1.20; I2: 57.1 %) and diastolic blood pressure (DBP) (WMD: -1.44; 95 % CI= -2.87, -0.02; P = 0.052; I2: 36.8 %; P: 0.105).
Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis
Phytotherapy research : PTR (2023) · Meta analysis
The standardized mean difference with 95% CI was calculated using fixed-effect or random-effect models.
A meta-analysis of randomized, double-blind, placebo-controlled trials for the effects of garlic on serum lipid profiles
Journal of the science of food and agriculture (2012) · Meta analysis · n=26
Compared with the placebo groups, serum TC and TG levels in the garlic group were reduced by 0.28 (95% CI, -0.45, -0.11) mmol L⁻¹ (P = 0.001) and 0.13 (95% CI, -0.20, -0.06) mmol L⁻¹ (P < 0.001), respectively.
Clinical Efficacy of Serenoa repens Versus Placebo Versus Alpha-blockers for the Treatment of Lower Urinary Tract Symptoms/Benign Prostatic Enlargement: A Systematic Review and Network Meta-analysis of Randomized Placebo-controlled Clinical Trials
European urology focus (2021) · Meta analysis · n=8564
In this network meta-analysis, we demonstrated that SeR did not show clinically meaningful improvement in LUTS and PF.
Serenoa repens (saw palmetto) for lower urinary tract symptoms/benign prostatic hyperplasia: A systematic review and meta-analysis of randomized controlled trials
BJU International (2018) · Meta analysis · n=5222
Significant improvement in maximum urinary flow rate vs placebo
Saw palmetto for BPH: A Cochrane review
Cochrane Database of Systematic Reviews (2012) · Systematic review · n=5000
Not superior to placebo in recent trials
Meta-analysis shows modest SBP reduction of ~4 mmHg and DBP reduction of ~1.4 mmHg. Effect size is relatively small compared to pharmaceutical interventions. Studies primarily used aged garlic extract forms.
Mixed evidence from meta-analyses. Some show significant improvement in maximum urinary flow rate vs placebo, while others show no clinically meaningful improvement. Hexanic lipidosterolic extracts (like Permixon) showed most consistent results. Effectiveness is conservative due to conflicting study outcomes.
AI-estimated from published studies. Interpret as directional guidance.
Aged Garlic Extract has a higher evidence score (9/10 vs 8/10) and wins in 1 of 3 categories.
For healthy aging, Saw Palmetto has a higher relevance score (90 vs 58).
No known interactions between Aged Garlic Extract and Saw Palmetto have been documented in our database. However, always consult a healthcare provider before combining supplements.