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Head-to-head evidence comparison — which supplement is right for you?
Aged Garlic Extract wins 2 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Likely helps
13 of 14 studies with measurable effects showed benefit.
Top outcomes
Verdict
Likely helps
4 of 4 studies with measurable effects showed benefit.
Top outcomes
600-1200mg aged garlic extract
With meals, Split into 2 doses
Kyolic Aged Garlic Extract (most studied)
500-2000mg dried berry or 200-500mg extract
Morning and/or early afternoon
Standardized extract (>2% schisandrins)
8-12 weeks
12+ weeks
4-8 weeks
2-4 weeks
1-2 weeks
4-8 weeks
Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials
Prostaglandins & other lipid mediators (2024) · Meta analysis · n=584
AGE tea supplementation reduces systolic blood pressure (SBP) (WMD: -4.03; %95CI: -6.87, -1.20; I2: 57.1 %) and diastolic blood pressure (DBP) (WMD: -1.44; 95 % CI= -2.87, -0.02; P = 0.052; I2: 36.8 %; P: 0.105).
Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis
Phytotherapy research : PTR (2023) · Meta analysis
The standardized mean difference with 95% CI was calculated using fixed-effect or random-effect models.
A meta-analysis of randomized, double-blind, placebo-controlled trials for the effects of garlic on serum lipid profiles
Journal of the science of food and agriculture (2012) · Meta analysis · n=26
Compared with the placebo groups, serum TC and TG levels in the garlic group were reduced by 0.28 (95% CI, -0.45, -0.11) mmol L⁻¹ (P = 0.001) and 0.13 (95% CI, -0.20, -0.06) mmol L⁻¹ (P < 0.001), respectively.
Treatment of chronic urticaria with traditional Chinese medicine: A systematic review, meta-analysis, and medication regularity
Medicine (2025) · Meta analysis · n=1192
TCM has great advantages in the treatment of CU, can effectively improve the symptoms, the curative effect is stable and safe, but there are still some deficiencies in the standardization of curative effect evaluation.
Changes in the Gut Microbiota after the Use of Herbal Medicines in Overweight and Obese Individuals: A Systematic Review
Nutrients (2023) · Systematic review
Herbal medicine modulates GM and is associated with increased genera in obese individuals.
Medicinal Plants and Their Impact on the Gut Microbiome in Mental Health: A Systematic Review
Nutrients (2022) · Systematic review
Only a few studies have been specifically designed to assess how herbal preparations affect MGBA-related targets or pathways.
Meta-analysis shows modest SBP reduction of ~4 mmHg and DBP reduction of ~1.4 mmHg. Effect size is relatively small compared to pharmaceutical interventions. Studies primarily used aged garlic extract forms.
Based on single RCT (n=80) showing reductions in fasting glucose, postprandial glucose, and insulin AUC. Effect limited to hyperglycemic individuals. Extract form and dosing schedule not fully specified.
AI-estimated from published studies. Interpret as directional guidance.
Aged Garlic Extract has a higher evidence score (9/10 vs 8.5/10) and wins in 2 of 3 categories.
For reduce inflammation, Aged Garlic Extract has a higher relevance score (90 vs 75).
No known interactions between Aged Garlic Extract and Schisandra have been documented in our database. However, always consult a healthcare provider before combining supplements.