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Head-to-head evidence comparison — which supplement is right for you?
Artichoke Extract vs Thiamine: they're closely matched on evidence (7 vs 7.5/10); the best pick depends on your goals. Take the 60-second quiz for a pick tailored to your goals.
Artichoke Extract and Thiamine are closely matched across evidence, studies, and safety.
Verdict
Likely helps
8 of 9 studies with measurable effects showed benefit.
Top outcomes
Verdict
Probably helps
7 of 12 studies with measurable effects showed benefit.
Top outcomes
600-1200mg extract daily
Before meals (especially fatty meals), Divided doses
Standardized leaf extract (2.5-5% cynarin)
50-100mg daily; 150-600mg benfotiamine for neuropathy
With food, Morning with other B vitamins
Benfotiamine (fat-soluble, higher bioavailability)
2-4 weeks
8-12 weeks
4-8 weeks
2-4 weeks
4-8 weeks
4-12 weeks
Lipid-lowering activity of artichoke extracts: A systematic review and meta-analysis
Critical reviews in food science and nutrition (2018) · Meta analysis · n=702
Quantitative data synthesis was performed using a random-effects model, with weighed mean difference (WMD) and 95% confidence interval (CI) as summary statistics.
Functional and Therapeutic Potential of Cynara scolymus in Health Benefits
Nutrients (2024) · Systematic review
This reduces the subsequent risk of developing conditions such as cancer, diabetes, and cardiovascular diseases.
The role of selected nutraceuticals in management of prediabetes and diabetes: An updated review of the literature. Part II
Phytotherapy research : PTR (2024) · Systematic review
The available evidence showed promising hypoglycemic effects of the nutraceuticals reviewed both for their efficacy and safety profile.
Dietary supplements for dysmenorrhoea
The Cochrane database of systematic reviews (2016) · Meta analysis · n=3101
Supplements versus other supplementsThere was no evidence of a difference in effectiveness between ginger and zinc sulphate (MD 0.02 points, 95% CI -0.58 to 0.62; one RCT, 101 women).
Evaluation of the Efficacy of the Addition of a Combination of Pyrimidine Nucleotides and Vitamin B1 and B12 to Standard Treatment in the Management of Painful Radiculopathy and in the Quality of Life of Patients
Nutrients (2024) · Rct · n=122
Both groups showed pain improvement, but the VAS reduction (control: 24.58 vs. experimental: 31.35) was not statistically significant.
Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Nutritional neuroscience (2023) · Systematic review · n=2256
Systematic review examining Thiamine efficacy
Based on meta-analysis of 702 subjects showing 17.6 mg/dL reduction in total cholesterol. Effect size is modest and may require 6+ weeks to manifest. Limited to artichoke leaf extract studies.
Based on limited RCT evidence showing VAS pain reduction with B-vitamin combinations. Effect magnitude conservative due to mixed statistical significance. Higher bioavailability forms like benfotiamine likely more effective than standard thiamine HCl.
AI-estimated from published studies. Interpret as directional guidance.
Both Artichoke Extract and Thiamine are closely matched — the best choice depends on your specific health goals.
No known interactions between Artichoke Extract and Thiamine have been documented in our database. However, always consult a healthcare provider before combining supplements.
The right pick depends on your goals. Answer a few quick questions for a personalised recommendation — or dig into the full evidence on each.