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Head-to-head evidence comparison — which supplement is right for you?
Evening Primrose Oil wins 3 of 3 categories. Both are solid choices — the best pick depends on your specific goals.
Verdict
Mostly mechanism / observational
Top outcomes
Verdict
Likely helps
4 of 5 studies with measurable effects showed benefit.
Top outcomes
Shared outcomes (1)
Outcomes where both Borage Oil and Evening Primrose Oil have evidence — compare verdict strength side-by-side.
1-3g/day borage oil providing roughly 240-1400mg GLA (higher GLA doses used in RA trials)
with-meals
Borage oil softgels (standardized GLA, PA-free)
1000-3000mg (providing 80-240mg GLA)
With meals containing fat
Softgels (cold-pressed oil)
3-6 months
Throughout use
6-12 weeks
First few weeks
2-3 cycles
2-3 cycles
8-12 weeks
Oral evening primrose oil and borage oil for eczema.
Cochrane Database Syst Rev (2013) · Systematic review · n=1596
27 studies (1596 participants); 8 assessed borage oil
Herbal therapy for treating rheumatoid arthritis.
Cochrane Database Syst Rev (2011) · Systematic review
22 studies included; 7 assessed GLA oils
Treatment of rheumatoid arthritis with gammalinolenic acid.
Ann Intern Med (1993) · Rct · n=37
Randomized, double-blind, placebo-controlled, 24-week trial, 37 patients
Oral evening primrose oil and borage oil for eczema
The Cochrane database of systematic reviews (2013) · Meta analysis · n=1596
With regard to the risk of bias, the majority of studies were of low risk of bias; we judged 67% of the included studies as having low risk of bias for random sequence generation; 44%, for allocation concealment; 59%, for blinding; and 37%, for other biases.
Breast pain
BMJ clinical evidence (2011) · Systematic review
Systematic review examining Evening Primrose Oil efficacy
Pre-eclampsia, eclampsia, and hypertension
BMJ clinical evidence (2011) · Systematic review
Systematic review examining Evening Primrose Oil efficacy
Based on meta-analysis of oral evening primrose oil for eczema (n=1596). Effect size is conservative given mixed quality of studies and modest clinical improvements typically seen.
AI-estimated from published studies. Interpret as directional guidance.
Evening Primrose Oil has a higher evidence score (7.5/10 vs 3.5/10) and wins in 3 of 3 categories.
For improve skin health, Evening Primrose Oil has a higher relevance score (60 vs 28).
No known interactions between Borage Oil and Evening Primrose Oil have been documented in our database. However, always consult a healthcare provider before combining supplements.